50763-70-7Relevant academic research and scientific papers
A unified, RCM anchored approach to spiro[4.5]decane-based sesquiterpenoids: Collective synthesis of (±)-α & β-vetispirenes, (±)-β-vetivone, (±)-agarospirol and (±)-hinesol
Athe, Sudhakar,Ghosh, Subhash,Mehta, Goverdhan
, p. 1570 - 1573 (2019)
Collective syntheses of five spiro[4.5]decane framework bearing sesquiterpenoids, namely, α & β-vetispirenes, β-vetivone, agarospirol and hinesol as well as formal synthesis of axenol and gleenol from a readily available precursor cyclohexanone-β-ketoester via the intermediacy of a versatile intermediate (2,10-dimethylspiro[4.5]dec-1-en-6-one) have been accomplished in a concise manner.
A New Spiro-annelation Procedure: Intramolecular Decarboxylative Alkylation of β-Keto-esters
Eilerman, Robert G.,Willis, Brian J.
, p. 30 - 32 (2007/10/02)
A new intramolecular decarboxylative alkylation route to spirocyclic ketones, and its application to the synthesis of (+/-)-β-vetivone and (+/-)-β-vetispirene are described.
