50775-02-5

Usage

Molecular structure

Brominated ketone with a seven-carbon chain and a ketone functional group

Main uses

Solvent, production of flavors and fragrances, intermediate in the synthesis of other organic compounds

Reactivity

Useful reagent in organic chemistry, particularly in the preparation of various brominated organic compounds

Physical properties

Strong characteristic odor, volatile and flammable liquid

Upstream product

• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 4117-09-3 7-bromo-hept-1-ene 

Downstream Products

• 65790-34-3 7-Dibenzylamino-heptan-2-one 
• 1312768-21-0 7-[2-(6-oxoheptyloxy)phenoxy]-2-heptanone 
• 1312768-22-1 1,2-bis[6,6-di(pyrrol-2-yl)heptyloxy]benzene 
• 334-20-3 (E)-9-oxo-dec-2-enoic acid 
• 560094-02-2 1,3-bis[6,6-di(pyrrol-2-yl)heptyloxy]-5-methylbenzene 
• 374109-37-2 (2-{2-[4-(6,6-difluoro-heptyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-2-yl]-ethoxy}-phenyl)-acetic acid methyl ester 
• 850032-92-7 isophthalic acid N,N'-bis[6,6-bis(1H-pyrrol-2-yl)heptyl]amide 
• 850032-90-5 N,N'-bis(6-oxoheptyl)isophthalamide 
• 71510-42-4 2-(6-oxoheptyl)isoindoline-1,3-dione 
• 37865-98-8 2-(5-bromopentyl)-2-methyl-[1,3]dioxolane 

Relevant academic research and scientific papers

Palladium-Catalyzed Aerobic Anti-Markovnikov Oxidation of Aliphatic Alkenes to Terminal Acetals

Terminal acetals were selectively synthesized from various unbiased aliphatic terminal alkenes and 1,2-, 1,3-, or 1,4-diols using a PdCl2(MeCN)2/CuCl catalyst system in the presence of p-toluquinone under 1 atm of O2 and mild reaction conditions. The slow addition of terminal alkenes suppressed the isomerization to internal alkenes successfully. Electron-deficient cyclic alkenes, such as p-toluquinone, were key additives to enhance the catalytic activity and the anti-Markovnikov selectivity. The halogen groups in the alkenes were found to operate as directing groups, suppressing isomerization and increasing the selectivity efficiently.

Asymmetric Enzymatic Hydration of Unactivated, Aliphatic Alkenes

The direct enantioselective addition of water to unactivated alkenes could simplify the synthesis of chiral alcohols and solve a long-standing challenge in catalysis. Here we report that an engineered fatty acid hydratase can catalyze the asymmetric hydration of various terminal and internal alkenes. In the presence of a carboxylic acid decoy molecule for activation of the oleate hydratase from E. meningoseptica, asymmetric hydration of unactivated alkenes was achieved with up to 93 % conversion, excellent selectivity (>99 % ee, >95 % regioselectivity), and on a preparative scale.