37865-98-8

Usage

Uses

Used in Pharmaceutical Synthesis:
2-(5-bromopentyl)-2-methyl-1,3-dioxolane is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the creation of new drug molecules with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 2-(5-bromopentyl)-2-methyl-1,3-dioxolane is employed as a building block for the development of new agrochemicals. Its chemical properties enable the production of compounds that can be used in crop protection and pest control.
Used in Organic Chemistry Research:
2-(5-bromopentyl)-2-methyl-1,3-dioxolane is utilized as a reagent in organic chemistry research, where it can be used to explore new reaction pathways and develop novel synthetic methods.

Upstream product

• 50775-02-5 7-bromo-2-heptanone 
• 107-21-1 ethylene glycol 
• 4224-70-8 6-bromohexanoic acid 
• 4117-09-3 7-bromo-hept-1-ene 

Downstream Products

• 334-20-3 (E)-9-oxo-dec-2-enoic acid 
• 1505448-12-3 C₂₅H₃₆N₂O₇ 
• 1505448-11-2 C₂₁H₂₉BrN₂O₅ 
• 1505448-10-1 C₂₁H₂₉ClN₂O₅ 
• 1505448-09-8 C₂₁H₂₉FN₂O₅ 
• 1505448-07-6 propyl 5-iodo-2-((8-(2-methyl-1,3-dioxolan-2-yl)oct-2-yn-1-yl)oxy)benzoate 
• 1505448-06-5 2-(8-(2-bromo-4-iodophenoxy)oct-6-yn-1-yl)-2-methyl-1,3-dioxolane 
• 1505448-05-4 2-(8-(2-chloro-4-iodophenoxy)oct-6-yn-1-yl)-2-methyl-1,3-dioxolane 
• 1505448-04-3 2-(8-(2-fluoro-4-iodophenoxy)oct-6-yn-1-yl)-2-methyl-1,3-dioxolane 
• 1505448-02-1 2-(8-(4-iodo-2-methoxyphenoxy)oct-6-yn-1-yl)-2-methyl-1,3-dioxolane 
• 1505448-01-0 2-(8-(4-iodo-2-methylphenoxy)oct-6-yn-1-yl)-2-methyl-1,3-dioxolane 
• 1505447-94-8 ethyl 1-(4-((8-(2-methyl-1,3-dioxolan-2-yl)oct-2-yn-1-yl)oxy)phenyl)hydrazine-1-carboxylate 
• 1505447-87-9 2-(8-(4-iodophenoxy)oct-6-yn-1-yl)-2-methyl-1,3-dioxolane 

Relevant academic research and scientific papers

INTEGRIN INHIBITORS

Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.

Tungsten(0) alkylidene complexes stabilized as pyridinium ylides: New aspects of their synthesis and reactivity

The interaction of dihydropyridines with alkoxycarbene complexes of tungsten has been shown to lead to pyridinium ylid complexes: this transformation has now been applied to the synthesis of a hydroxyl-containing ylid complex by ring-opening of the pentacarbonyl (2-oxacyclopentylidene) tungsten(0) complex and to the synthesis of a series of chiral ylid complexes both from chiral and non-chiral carbene complexes by the use of dihydropyridines and dihydronicotines, respectively. The transfer of the alkylidene moiety of these complexes to nucleophilic olefins will be outlined and discussed. Especially relevant is the interaction of these pyridinium ylid complexes with unsaturated substrates such as dihydropyridines, enamines, and β-alkoxy bis(trimethyl-silyl) ketene acetals. This latter reaction leads to conjugated carboxylic acids, and has been be applied to a new synthesis of a honey bee pheromone, the queen substance.

Efficient and Convergent Synthesis of (R)-(-)-10-Methyltridecan-2-one, the Sex Pheromone of the Spotted Cucumber Beetle, by Iron-Mediated Chirality Transfer

The synthesis of (R)-(-)-10-methyltridecan-2-one, the female sex pheromone of the southern corn root worm (Diabrotica undecimpunctata howardi Barber) in high enantiomeric purity (ee >/= 99percent) and excellent overall yields (75percent, five step

Camphorsulfonamide-Shielded, Asymmetric 1,4-Additions and Enolate Alkylations; Synthesis of a Southern Corn Rootworm Pheromone

Using readily accessible 10-sulfonamido-isoborneols as regenerable, chiral auxiliaries, highly face-selective C-C-bond formations at Cα and Cβ of carboxylates could be conveniently achieved.Thus, conjugated additions of RCu to enoates (1->2) furnished, after saponification, β-substituted carboxylic acids 3 in 94-98 percent e.e.Similarly, propionates 12 yielded after deprotonation, enolate alkylation, and reductive ester cleveage the (R)-alcohols 15 in 78-98 percent e.e.The acid (+)-3e was converted to the pheromone (-)-11.