508234-94-4

Usage

Uses

Used in Pharmaceutical Industry:
N-Biotinyl-N’-(N-Boc-S-trityl)cysteinyl Ethylenediamine is used as an intermediate for the synthesis of N-Biotinyl-N'-cysteinyl Ethylenediamine, which is an essential component in the development of pharmaceutical products. Its role in the synthesis process is crucial for creating compounds with specific therapeutic properties.
Used in Chemical Synthesis:
As a white solid with distinct chemical properties, N-Biotinyl-N’-(N-Boc-S-trityl)cysteinyl Ethylenediamine is also used in various chemical synthesis processes. Its unique structure allows it to be a valuable building block for creating a wide range of compounds with different applications in various industries.
Used in Research and Development:
N-Biotinyl-N’-(N-Boc-S-trityl)cysteinyl Ethylenediamine is utilized in research and development for its potential applications in creating new compounds and materials. Its unique properties make it an interesting subject for scientific exploration and innovation, potentially leading to breakthroughs in various fields.

Upstream product

• 21947-98-8 N-tert-butyloxycarbonyl-S-trityl-L-cysteine 
• 111790-37-5 N-biotinyl-1,2-diaminoethane 
• 225797-46-6 {2-[5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-ethyl}-carbamic acid tert-butyl ester 
• 111822-45-8 (+)-biotinyl-2-aminoethan-1-aminium chloride 

Relevant academic research and scientific papers

Intein-mediated biotinylation of proteins and its application in a protein microarray

We report here the first example using an intein-mediated expression system to generate biotinylated proteins suitable for immobilization onto avidin-functionalized glass slides. With this novel array, proteins are site-specifically immobilized on the gla

Efficient Delivery of Quantum Dots into the Cytosol of Cells Using Cell-Penetrating Poly(disulfide)s

Quantum dots (QDs) are extremely bright, photostable, nanometer particles broadly used to investigate single molecule dynamics in vitro. However, the use of QDs in vivo to investigate single molecule dynamics is impaired by the absence of an efficient way

A ribozyme with michaelase activity: synthesis of the substrate precursors.

The ability to generate RNA molecules that can catalyze complex organic transformations not only facilitates the reconstruction and plausibility of possible prebiotic reaction pathways but is also crucial for elucidating the potential of the application of RNA catalysts in organic syntheses. Iterative RNA selection previously identified a ribozyme that catalyzes the Michael addition of a cysteine thiol to an alpha,beta-unsaturated amide. This reaction is chemically similar to the rate limiting step of the thymidylate synthase reaction, which is the corresponding reaction of a cysteine thiol to the double-bond of the uracil nucleobase. Here we provide a detailed description of the synthesis of the ribozyme substrates and the substrate oligonucleotides used for its characterization and the investigation of the background reaction. We also describe the further characterization of the ribozyme with respect to substrate specificity. We show that the thiol group of the cysteine nucleophile is essential for the reaction to proceed. When substituted for a thiomethyl group, no reaction takes place.

Intein-mediated synthesis of proteins containing carbohydrates and other molecular probes

We report here the use of an intein-mediated protein ligation strategy for the synthesis of glycoproteins and proteins containing various molecular probes. Several simple cysteine derivatives are synthesized and used as nucleophiles for specific incorpora