21947-98-8

Basic information

• Product Name: N-Boc-S-Trityl-L-cysteine
• Synonyms: Nα-Boc-S-trityl-L-cysteine, N-(tert-Butoxycarbonyl)-S-trityl-L-cysteine;Boc-S-Trityl-Cys-OH;N-(tert-Butyloxycarbonyl)-S-trityl-L-cysteine;N-[(1,1-Dimethylethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine;N-Boc-S-Trityl-L-Cys-OH;BOC-S-trityl-L-cysteine,99%;2-(tert-butoxycarbonylamino)-3-[tri(phenyl)methylthio]propionic acid;2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[tri(phenyl)methylsulfanyl]propanoic acid
• CAS NO: 21947-98-8
• Molecular Formula: C₂₇H₂₉NO₄S
• Molecular Weight: 463.59
• EINECS: 244-674-6
• Product Categories: Cysteine [Cys, C];Boc-Amino Acids and Derivative;Boc-Amino acid series;Amino Acid Derivatives;Amino Acids
• Mol File: 21947-98-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 143-146 °C(lit.)
• Boiling Point: 610.9 °C at 760 mmHg
• Flash Point: 323.3 °C
• Appearance: White to yellow crystalline powder
• Density: 1.2 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: 2-8°C
• PKA: 3.82±0.10(Predicted)
• BRN: 2028965
• CAS DataBase Reference: N-Boc-S-Trityl-L-cysteine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-S-Trityl-L-cysteine(21947-98-8)
• EPA Substance Registry System: N-Boc-S-Trityl-L-cysteine(21947-98-8)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 21947-98-8(Hazardous Substances Data)

Usage

Chemical Properties

White to yellow crystalline powder

InChI:InChI=1/C27H29NO4S/c1-26(2,3)32-25(31)28-23(24(29)30)19-33-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,28,31)(H,29,30)/t23-/m1/s1

Upstream product

• 103213-32-7 N-(9-fluorenylmethoxycarbonyl)-S-trityl-L-cysteine 
• 109-89-7 diethylamine 
• 52-90-4 L-Cysteine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 76-83-5 trityl chloride 
• 76-84-6 triphenylmethyl alcohol 
• 2799-07-7 S-trityl-L-cysteine 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 52-89-1 l-cysteine hydrochloride 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 

Downstream Products

• 33642-47-6 Boc-Cys(Trt)-ONp 
• 70903-37-6 (2S,3S)-2-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoic acid methyl ester 
• 52071-18-8 N-(tert-butyloxycarbonyl)-S-(triphenylmethyl)-L-cysteinylglycine methyl ester 
• 160876-88-0 [2-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-acetylamino]-acetic acid benzyl ester 
• 92278-71-2 Boc-Cys(Trt)-D-Val-O-Bzl 
• 40472-53-5 BOCCys(Trit)ProOH 
• 139924-65-5 ethyleneglycol bis ester of N-Boc S-Trt cysteine 
• 145397-00-8 (Nα'-9-fluorenylmethyloxycarbonyl-Nα''-tert.butoxycarbonyl-cystine-O'-benzyl ester) 
• 89028-32-0 N-tert.-Butyloxycarbonyl-S-trityl-L-cysteinyl-S-diphenylmethyl-L-cysteinyl-L-alanin-methylester 
• 160876-89-1 (S)-2-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionic acid benzyl ester 

Relevant articles and documents

CGG repeat DNA assisted dimerization of CGG/CGG binding molecule through intermolecular disulfide formation

A new DNA binding small molecule, NCD-CC is reported. NCD-CC has a NCD domain, which recognizes the G-G mismatch in a CGG/CGG triad, and a cysteinylcystein (CC) moiety. Dimerization of NCD-CC through intermolecular disulfide bond formation was accelerated in the presence of CGG repeat DNA.

Tripeptide-induced modulation of mesenchymal stem cell biomechanics stimulates proliferation and wound healing

We demonstrate the ability of two tripeptides to promote proliferation and modulate the mechanical properties of human mesenchymal stem cells (hMSCs). Notably, Young's modulus of peptide-treated hMSCs was found to be ～2 fold higher compared to the control group. These peptides promoted wound healing in hMSCs, without stimulating osteogenic and adipogenic differentiation, thus showing high potential in vascular tissue engineering applications.

Aminothiol compound, preparation method of aminothiol compound and application of aminothiol compound in radiation protection

The invention discloses an aminothiol compound, a preparation method of the aminothiol compound and application of the aminothiol compound in radiation protection. The compound has a structure shown in the formula I in the description, wherein A1 is selected from -C(O)NR8-, -S(O)2-NR8-, -S(O)NR8- and -R7-NR8-, A2 is selected from carbonyl, sulfonyl, sulfinyl and substituted or unsubstituted C1-6 alkyl, R1, R2, R5 and R6 can be the same or not and are selected from hydrogen and substituted or unsubstituted C1-C5 alkyl or hetero alkyl, n is an integer from 0 to 20000, R3 and R4 are independently selected from hydrogen, X and substituted or unsubstituted C1-6 alkyl, X is selected from F, Cl, Br and I, R7 is selected from substituted or unsubstituted C1-C6 alkyl, and R8 is selected from hydrogen and substituted or unsubstituted C1-C6 alkyl. The compound has the effect of reducing biological injury caused by ionizing radiation and also has the effects of prolonging the lifetime of radiated animals and increasing the survival rate of the radiated animals.