50827-54-8

Usage

Uses

Used in Organic Synthesis:
2,4,6-Trimethylbenzenesulfinic acid is used as a reactant in organic synthesis for the preparation of various derivatives. Its presence of the sulfinic acid functional group allows it to participate in a range of chemical reactions, making it a valuable building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4,6-trimethylbenzenesulfinic acid is utilized as a key intermediate in the synthesis of bioactive compounds. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2,4,6-Trimethylbenzenesulfinic acid also finds applications in the agrochemical industry, where it is employed in the synthesis of crop protection agents. Its role in creating effective and environmentally friendly pesticides highlights its importance in agricultural chemistry.
Used as a Reducing Agent:
Due to the presence of the sulfinic acid functional group, 2,4,6-trimethylbenzenesulfinic acid can act as a reducing agent in certain chemical reactions. This property further expands its utility in various chemical processes and applications.

Upstream product

• 21991-08-2 2-Mesitylsulfonylthiophen 
• 576-83-0 2,4,6-trimethylphenyl bromide 
• 73766-65-1 2,4,6-trimethylbenzenesulfinyl chloride 

Downstream Products

• 55757-31-8 1,3,5-trimethyl-4-thiocyanatobenzene 
• 118450-86-5 2,2-dimethyl-1-(p-nitrophenyl)propyl mesityl sulfate 
• 82012-43-9 ethyl N-(2-mesitylenesulfonylmethyl)carbamate 
• 19822-09-4 1-mesitylsulfonylacetone 
• 3112-82-1 (2,4,6-trimethylphenyl) phenyl sulfone 
• 1667-01-2 2,4,6-Trimethylacetophenone 

Relevant academic research and scientific papers

Iodine/TBHP-Promoted One-Pot Deoxygenation and Direct 2-Sulfonylation of Quinoline N-Oxides with Sodium Sulfinates: Facile and Regioselective Synthesis of 2-Sulfonylquinolines

A highly efficient iodine/TBHP-mediated one-pot deoxygenative and regioselective 2-sulfonylation of quinoline N-oxides with sodium sulfinate salts has been developed. This metal-, base-, and phosphorus-free protocol employs readily accessible and easy-to-handle reagents and can be conveniently carried out at room temperature under mild conditions, providing an alternative access to a series of 2-sulfonylquinolines and other related heteroaryl sulfone products in moderate-to-excellent yields within a short reaction time.

Method for preparing aryl sulfinate

The invention provides a method for preparing an aryl sulfinate compound through the reaction of diaryl iodonium salt and sodium formaldehyde sulfoxylate.At room temperature, the diaryl iodonium salt reacts with the sodium formaldehyde sulfoxylate for 10-120 minutes to generate the corresponding aryl sulfinate compound.The method has the advantages that the reaction conditions are mild, the used reagents re easy to obtain, the application range of a substrate is wide, operation is simple, reaction is quick, and the like.

Synthesis of sodium aryl sulfinates from aryl bromides employing 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct (DABSO) as a bench-stable, gas-free alternative to SO2

A convenient two-step protocol for the synthesis of sodium aryl sulfinates from aryl bromides and the SO2 surrogate 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct (DABSO) has been developed. A wide range of aryl bromides with respect to electronic properties were employed to give the corresponding sodium arylsulfinates in good to excellent yields. The protocol is especially efficient for electron poor aryl bromides which are often difficult to prepare using existing methods.