50827-54-8

Basic information

• Product Name: 2,4,6-trimethylbenzenesulfinic acid
• CAS NO: 50827-54-8
• Molecular Formula: C₉H₁₁O₂S*Na
• Molecular Weight: 184.2554
• Mol File: 50827-54-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 363.4°C at 760 mmHg
• Flash Point: 173.6°C
• Density: 1.26g/cm³
• Vapor Pressure: 6.45E-06mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 2,4,6-trimethylbenzenesulfinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-trimethylbenzenesulfinic acid(50827-54-8)
• EPA Substance Registry System: 2,4,6-trimethylbenzenesulfinic acid(50827-54-8)

Safety Data

• Hazardous Substances Data: 50827-54-8(Hazardous Substances Data)

Usage

General Description

2,4,6-trimethylbenzenesulfinic acid is a chemical compound with the formula C9H10O2S. It is a sulfinic acid that contains a benzene ring with three methyl groups attached to it. 2,4,6-trimethylbenzenesulfinic acid is commonly used as a reactant in organic synthesis and as a building block for the preparation of various derivatives. It can also act as a reducing agent due to the presence of the sulfinic acid functional group. Additionally, 2,4,6-trimethylbenzenesulfinic acid has applications in the pharmaceutical and agrochemical industries, where it is utilized in the synthesis of various bioactive compounds and crop protection agents.

Upstream product

• 73766-65-1 2,4,6-trimethylbenzenesulfinyl chloride 
• 576-83-0 2,4,6-trimethylphenyl bromide 
• 21991-08-2 2-Mesitylsulfonylthiophen 

Downstream Products

• 55757-31-8 1,3,5-trimethyl-4-thiocyanatobenzene 
• 118450-86-5 2,2-dimethyl-1-(p-nitrophenyl)propyl mesityl sulfate 
• 1667-01-2 2,4,6-Trimethylacetophenone 
• 3112-82-1 (2,4,6-trimethylphenyl) phenyl sulfone 
• 19822-12-9 1-diazo-1-[(2,4,6-trimethylbenzene)sulfonyl]-2-propanone 
• 19822-13-0 Acetyl-(2,4,6-trimethyl-phenylsulfonyl)-formaldehyd-hydrazon 
• 19822-18-5 (2,4,6-Trimethyl-phenylsulfonyl)-formaldehyd-hydrazon 
• 81992-59-8 α-benzoyl-α-(2-mesitylenesulfonyl)diazomethane 
• 81992-62-3 tert-butyl 2-mesitylenesulfonyl-2-phenylacetate 
• 81992-57-6 ethyl N-(2-mesitylenesulfonylmethyl)-N-nitrosocarbamate 
• 81992-61-2 2-benzoyl-5,7-dimethyl-2,3-dihydrobenzothiophene-1,1-dioxide 
• 81992-58-7 2-mesitylenesulfonyldiazomethane 
• 5350-76-5 1-phenyl-2-(2,4,6-trimethylphenyl)ethanone 
• 19822-09-4 1-mesitylsulfonylacetone 

Relevant articles and documents

Iodine/TBHP-Promoted One-Pot Deoxygenation and Direct 2-Sulfonylation of Quinoline N-Oxides with Sodium Sulfinates: Facile and Regioselective Synthesis of 2-Sulfonylquinolines

A highly efficient iodine/TBHP-mediated one-pot deoxygenative and regioselective 2-sulfonylation of quinoline N-oxides with sodium sulfinate salts has been developed. This metal-, base-, and phosphorus-free protocol employs readily accessible and easy-to-handle reagents and can be conveniently carried out at room temperature under mild conditions, providing an alternative access to a series of 2-sulfonylquinolines and other related heteroaryl sulfone products in moderate-to-excellent yields within a short reaction time.

Synthesis of sodium aryl sulfinates from aryl bromides employing 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct (DABSO) as a bench-stable, gas-free alternative to SO2

A convenient two-step protocol for the synthesis of sodium aryl sulfinates from aryl bromides and the SO2 surrogate 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct (DABSO) has been developed. A wide range of aryl bromides with respect to electronic properties were employed to give the corresponding sodium arylsulfinates in good to excellent yields. The protocol is especially efficient for electron poor aryl bromides which are often difficult to prepare using existing methods.