5084-98-0

Basic information

• Product Name: Z-LEU-GLY-OME
• Synonyms: Z-LEUCYL-L-GLYCINE METHYL ESTER;Z-LEU-GLY-OME;N-CBZ-LEU-GLY METHYL ESTER;N-(N-Phenylmethoxycarbonyl-L-leucyl)glycine methyl ester;2-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]acetic acid methyl ester;methyl 2-[[4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]acetate;methyl 2-[[4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]ethanoate
• CAS NO: 5084-98-0
• Molecular Formula: C₁₇H₂₄N₂O₅
• Molecular Weight: 336.38
• Mol File: 5084-98-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 516.4 °C at 760 mmHg
• Flash Point: 266.1 °C
• Appearance: /
• Density: 1.146 g/cm³
• Vapor Pressure: 9.01E-11mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: -15°C
• CAS DataBase Reference: Z-LEU-GLY-OME(CAS DataBase Reference)
• NIST Chemistry Reference: Z-LEU-GLY-OME(5084-98-0)
• EPA Substance Registry System: Z-LEU-GLY-OME(5084-98-0)

Safety Data

• Hazardous Substances Data: 5084-98-0(Hazardous Substances Data)

Usage

General Description

Z-Leu-Gly-Ome, also known as carbobenzoxy-L-leucyl-glycine methyl ester, is a chemical compound often utilized in biochemical research. Z-LEU-GLY-OME is particularly known for its role as a substrate in enzyme-catalyzed reactions, specifically involving proteolytic enzymes such as elastase and cathepsin G. Z-Leu-Gly-Ome is a dipeptide with a molecular formula of C16H24N2O5 and a molecular weight of 320.37 g/mol. Z-LEU-GLY-OME is generally available in a stable, solid form and should be stored in a cool, dry location to maintain its integrity. However, like many chemicals, it poses potential risks if not handled correctly, and it's important to use protective equipment when handling Z-Leu-Gly-Ome.

InChI:InChI=1/C17H24N2O5/c1-12(2)9-14(16(21)18-10-15(20)23-3)19-17(22)24-11-13-7-5-4-6-8-13/h4-8,12,14H,9-11H2,1-3H3,(H,18,21)(H,19,22)

Upstream product

• 3397-35-1 Z-L-leucine hydroxysuccinimide ester 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 61-90-5 L-leucine 
• 501-53-1 benzyl chloroformate 
• 87024-12-2 (S)-1-(2'-benzyloxycarbonylamino-4'-methylpentanoyl)-3,5-dimethylpyrazole 
• 616-34-2 methoxycarbonylmethylamine 
• 53363-87-4 N-(benzyloxycarbonyl)leucine dicyclohexylamine salt 
• 2018-66-8 Z-Leu-OH 

Downstream Products

• 1361509-42-3 (S)-methyl 2-(2-(benzyloxycarbonylamino)-4-methylpentaneselenoamido)acetate 
• 107540-40-9 Ac-Leu-2-Ala-Ser-Leu-Gly-OMe 
• 107540-39-6 {(S)-2-[(S)-2-Amino-3-(diphenoxy-phosphoryloxy)-propionylamino]-4-methyl-pentanoylamino}-acetic acid methyl ester; hydrochloride 
• 107540-38-5 Z-Ser-Leu-Gly-OMe 
• 107540-60-3 Tr-Ser-Leu-Gly-OMe 
• 107540-59-0 Z-Ser(O-mesyl)-Leu-Gly-OMe 
• 107540-61-4 Tr-Azy-Leu-Gly-OMe 
• 107540-26-1 Z-Ser-Leu-Gly-OMe 
• 19739-60-7 Cbz-leucylglycyl hydrazide 
• 108061-14-9 [5-(1-Benzyloxycarbonylamino-3-methyl-butyl)-tetrazol-1-yl]-acetic acid methyl ester 
• 2706-38-9 N-(N-benzyloxycarbonyl-L-leucyl)-glycine 

Relevant articles and documents

Synthesis of selenoxo peptides and oligoselenoxo peptides employing LiAlHSeH

Synthesis of selenoxo peptides by the treatment of Nα- protected peptide esters with a combination of PCl5 and LiAlHSeH is delineated. The method is simple, high-yielding, and free from racemization. Thus obtained selenoxo peptides are used as units for N-terminal chain extension through Nα-deprotection/coupling to yield peptide-selenoxo peptide hybrids. Multiple selenation is demonstrated by conversion of two peptide bonds of tripeptides into selenoxo peptide bonds. Amino acid derived arylamides are also converted into aryl selenoamides. C6H 5-CSeNH-Val-OMe 8f is obtained as single crystal, and its structure was determined through X-ray diffraction study.

SYNTHESIS OF FRAGMENTS OF THE VP1 PROTEIN OF TYPE A22 FOOT-AND-MOUTH DISEASE VIRUS. SYNTHESIS OF FRAGMENTS 134-139, 134-145, 140-145, 150-155, AND 150-159

Fragments of peptides of the amino acid sequences (134-145) and (150-159) of the VP1 protein of the type A22 foot-and-mouth disease (FMD)virus have been synthesized by the classical methods of peptide chemistry.Oligopeptides were obt

SYNTHESIS AND PROPERTIES OF CARBOXYLIC ACID PYRAZOLIDES

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