50848-00-5

Upstream product

• 120-82-1 1,2,4-Trichlorobenzene 
• 95-50-1 1,2-dichloro-benzene 

Downstream Products

• 104254-99-1 2,3,4-Trichloro-6-(3,4-dichloro-phenoxy)-phenol 
• 155999-97-6 2,3,3',4',5,6-hexachlorodiphehyl ether 
• 56348-72-2 3,3',4,4'-tetrachlorodiphenyl ether 
• 130892-66-9 2,3',4',6-tetrachlorodiphenyl ether 
• 83992-70-5 2,3,3',4,4',5,6-heptachlorodiphenyl ether 
• 109828-22-0 2,3,3',4,4',5-pentachlorodiphenyl ether 
• 3380-33-4 5-Chloro-2-(3,4-dichloro-phenoxy)-phenol 

Relevant academic research and scientific papers

AM1 and Single-crystal X-ray Diffraction Study of the Conformational Properties of Chlorinated Diphenyl Ethers

Structural and conformational properties of 11 polychlorinated diphenyl ethers (PCDEs) 1-11 and thyroxine derivative 12 were studied by the semiempirical AM1 method.In addition, the molecular structures of six PCDEs 1-6 were solved by X-ray crystallograph

Cephem and cepham compounds

This invention relates to new cephem and cepham compounds of high antimicrobial activity of the formula: STR1 wherein R1 is amino or a protected amino, R2 is hydrogen, acyl, aryl which may be substituted with suitable substituent(s), lower alkyl substituted with suitable substituent(s), lower alkenyl, lower alkynyl, cycloalkyl which may be substituted with suitable substituent(s), cyclo(lower)alkenyl, or S or O containing 5-membered heterocyclic group substituted with oxo group(s), R3 is hydrogen or lower alkyl, R4 is hydrogen, acyloxy(lower)alkyl; acylthio(lower) alkyl; pyridinium(lower)alkyl which may be substituted with suitable substituent(s); a heterocyclicthio(lower)alkyl which may be substituted with suitable substituent(s); lower alkyl;l halogen; hydroxy; thiazolium(lower)alkyl which may be substituted with suitable substituent(s); or lower alkoxy; R5 is carboxy or a protected carboxy, wherein R5 is COO- when R4 is pyridinium(lower)alkyl which may be substituted with suitable substituent(s) or thiazolium(lower)alkyl which may be substituted with suitable substituent(s), and the heavy solid line means single or double bond; and pharmaceutically acceptable salt thereof.

Cephem and cepham compounds

This invention relates to novel 7-thiadiazol-oxyimino-3-cephem and cepham 4-carboxylic acid compounds of high antimicrobial activity.

7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds

This invention relates to new cephem and cepham compounds of high antimicrobial activity, and more particularly to new 7-amino-thiadiazole oxyimino derivatives of cephem and cepham compounds.

Cephem and cepham compounds

7-Substituted-3-cephem and cepham-4-carboxylic acids represented by the following formula (I): STR1 wherein R1 is amino or a protected amino, R2 is hydrogen, acyl, aryl which may be substituted with suitable substituent(s), lower alkyl substituted with suitable substituent(s), lower alkenyl, lower alkynyl, cycloalkyl which may be substituted with suitable substituent(s), cyclo(lower)alkenyl, or S or O containing 5-membered heterocyclic group substituted with oxo group(s), R3 is hydrogen or lower alkyl, R4 is hydrogen; acyloxy(lower)alkyl); acylthio(lower)alkyl; pyridinium(lower)alkyl which may be substituted with suitable substituent(s); a heterocyclicthio(lower)alkyl which may be substituted with suitable substituent(s); lower alkyl; halogen; or hydroxy; and, R5 is carboxy or a protected carboxy, wherein R5 is COO- when R4 is pyridinium(lower)alkyl which may be substituted with suitable substituent(s), and the heavy solid line means single or double bond, are useful as antibiotics.

7-Amino-thia-diazole oxyimino derivatives of cephem and cephem compounds

7-Substituted-3-cephem and cepham-4-carboxylic acids of formula (I) STR1 wherein R1 is amino or a protected amino, R2 is hydrogen, acyl, aryl which may be substituted with suitable substituent(s), lower alkyl substituted with suitable substituent(s), lower alkenyl, lower alkynyl, cycloalkyl which may be substituted with suitable substituent(s), cyclo(lower)alkenyl, or S- or O-containing 5-membered heterocyclic group substituted with oxo group(s). R3 is hydrogen or lower alkyl, R4 is hydrogen; acyloxy(lower)alkyl; acylthio(lower)alkyl pyridinium(lower)alkyl which may be substituted with suitable substituent(s); a heterocyclicthio(lower)alkyl which may be substituted with suitable substituent(s); lower alkyl; halogen; or hydroxy; and R5 is carboxy or a protected carboxy wherein R5 is COO-- when R4 is pyridinium(lower)alkyl which may be substituted with suitable substituent(s), and the heavy solid line means single or double bond, have useful antibiotic properties.