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p-TosOH*H-Met-ODpm is a complex chemical compound consisting of three main components: p-toluenesulfonic acid (p-TosOH), hydroxyl group (H), and a protected methionine derivative (Met-ODpm). p-Toluenesulfonic acid is a strong acid used as a catalyst in various organic reactions, while the hydroxyl group is a functional group that can participate in various chemical reactions. The protected methionine derivative, Met-ODpm, is a modified form of the amino acid methionine, where the sulfur atom is protected by a diphenylmethyl (Dpm) group. This protection is crucial for preventing unwanted side reactions during peptide synthesis. Overall, p-TosOH*H-Met-ODpm is a multifunctional chemical that can be used in various applications, such as peptide synthesis and organic transformations, due to its combination of acidic, hydroxyl, and protected amino acid functionalities.

5088-86-8

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5088-86-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5088-86-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,8 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5088-86:
(6*5)+(5*0)+(4*8)+(3*8)+(2*8)+(1*6)=108
108 % 10 = 8
So 5088-86-8 is a valid CAS Registry Number.

5088-86-8Downstream Products

5088-86-8Relevant academic research and scientific papers

A Novel Preparation of Amino Acid Diphenylmethyl Esters and Their Application in Peptide Synthesis

Barlos, Kleomenis,Kallitsis, John,Mamos, Petros,Patrianakou, Stella,Stavropoulos, Georg

, p. 633 - 636 (2007/10/02)

Trityl amino acid diphenylmethyl esters 2 were prepared by Mitsunobu condensation of tritylamino acids 1 with diphenylmethanol using excess triphenylphosphane and diethyl azodicarboxylate.The esters 2 were converted into the corresponding p-toluenesulfonates 3 on treatment with p-toluenesulfonic acid.The removal of the N-trityl group in the presence of the diphenylmethyl ester group is studied by the preparation of leucine-enkephalin (12).Best selectivity is obtained when 1-hydroxybenzotriazole in trifluoroethanol is used as detritylation reagent.

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