50899-16-6

Basic information

• Product Name: 4-Isoxazolecarboxylicacid,3-phenyl-,methylester(9CI)
• Synonyms: 4-Isoxazolecarboxylicacid,3-phenyl-,methylester(9CI)
• CAS NO: 50899-16-6
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203.19
• Product Categories: ISOXAZOLE
• Mol File: 50899-16-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Isoxazolecarboxylicacid,3-phenyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylicacid,3-phenyl-,methylester(9CI)(50899-16-6)
• EPA Substance Registry System: 4-Isoxazolecarboxylicacid,3-phenyl-,methylester(9CI)(50899-16-6)

Safety Data

• Hazardous Substances Data: 50899-16-6(Hazardous Substances Data)

Upstream product

• 922-67-8 propynoic acid methyl ester 
• 932-90-1 Benzaldoxime 
• 1402812-40-1 C₂₃H₁₉NO 
• 1402704-06-6 (Z)-1-phenyl-1-buten-1-ylboronic acid 
• 1821-34-7 N-chlorobenzamide 
• 698-16-8 benzohydroximoyl chloride 
• 934-16-7 phenylhydroxamoyl chloride 
• 1104461-74-6 methyl 3-(p-nitrobenzoyloxy)acrylate 
• 50899-13-3 3-phenyl-4,5-dihydro-isoxazole-4-carboxylic acid methyl ester 

Downstream Products

• 288404-37-5 (3-phenylisoxazol-4-yl)methanol 
• 18718-84-8 3-phenyl-4-isoxazolecarboxylic acid 

Relevant articles and documents

Preparation and rearrangement of N-vinyl nitrones: Synthesis of spiroisoxazolines and fluorene-tethered isoxazoles

N-Vinyl nitrones derived from fluorenone have been prepared via a copper-mediated coupling between fluorenone oxime and vinyl boronic acids. These compounds undergo subsequent rearrangement and addition reactions that are distinct from the traditional [3 + 2] cycloaddition reactivity of nitrones. Thermal rearrangements of fluorenone N-vinyl nitrones give spiroisoxazolines, while treatment with alkynes provides fluorene-tethered isoxazoles. The scope and limitations of the preparation of fluorenone N-vinyl nitrones and their subsequent rearrangement and addition reactions are discussed.

Conversion of oximes to carbonyl compounds by triscetylpyridinium tetrakis(oxodiperoxotungsto) phosphate (PCWP)-mediated oxidation with hydrogen peroxide

Aromatic and aliphatic oximes have been deoximated in chloroform-water to the corresponding aldehydes with dilute hydrogen peroxide and triscetylpyridinium tetrakis (oxodiperoxotungsto) phosphate as catalyst. The presence of dipolarophiles in the reaction mixtures allows a competitive reaction that converts oximes into isoxazole and isoxazoline derivatives via the intermediate formation of nitrile oxide species.

ISOXAZOLECARBOXAMIDE DERIVATIVES

-