50907-57-8

Basic information

• Product Name: 2-CHLORO-6-NITROBENZENEMETHANOL
• Synonyms: 2-CHLORO-6-NITROBENZYL ALCOHOL;2-CHLORO-6-NITROBENZENEMETHANOL;RARECHEM AL BD 0678;(2-chloro-6-nitrophenyl)methanol
• CAS NO: 50907-57-8
• Molecular Formula: C₇H₆ClNO₃
• Molecular Weight: 187.58
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 50907-57-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 56 °C
• Boiling Point: 306.1°C at 760 mmHg
• Flash Point: 138.9°C
• Appearance: /
• Density: 1.476g/cm³
• Vapor Pressure: 0.000345mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.40±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-6-NITROBENZENEMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-NITROBENZENEMETHANOL(50907-57-8)
• EPA Substance Registry System: 2-CHLORO-6-NITROBENZENEMETHANOL(50907-57-8)

Safety Data

• Hazardous Substances Data: 50907-57-8(Hazardous Substances Data)

Usage

General Description

2-Chloro-6-nitrobenzenemethanol is a chemical compound with the molecular formula C7H6ClNO3. It is a white to light yellow solid that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-Chloro-6-nitrobenzenemethanol has potential applications as an antifungal and antibacterial agent. It is also used as a building block for the synthesis of other organic compounds. 2-Chloro-6-nitrobenzenemethanol is considered to be hazardous and should be handled with care, as it may cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C7H6ClNO3/c8-6-2-1-3-7(9(11)12)5(6)4-10/h1-3,10H,4H2

Upstream product

• 83-42-1 6-chloro-2-nitrotoluene 
• 6361-22-4 2-chloro-6-nitrobenzaldehyde 
• 56433-01-3 2-chloro-6-nitrobenzyl bromide 

Downstream Products

• 5344-49-0 2-chloro-6-nitrobenzoic acid 
• 193970-86-4 C₂₁H₅ClF₁₀N₄O₅S 
• 56433-01-3 2-chloro-6-nitrobenzyl bromide 
• 89892-65-9 2,β-Dinitro-6-chlor-styrol 
• 206882-41-9 5-(2-chloro-6-nitrobenzyloxy)isoquinoline 
• 206883-06-9 5-(2-amino-6-chlorobenzyloxy)isoquinoline 
• 206884-02-8 5-(2-amino-3,6-dichlorobenzyloxy)isoquinoline 
• 258842-75-0 2-chloro-6-nitrobenzyl methanesulfonate 
• 6361-22-4 2-chloro-6-nitrobenzaldehyde 

Relevant articles and documents

IRIDIUM-BASED CATALYSTS FOR HIGHLY EFFICIENT DEHYDROGENATION AND HYDROGENATION REACTIONS IN AQUEOUS SOLUTION AND APPLICATIONS THEREOF

A series of iridium-based catalysts for dehydrogenation of formic acid, and hydrogenation using formic acid as the hydrogen source, and the process using the catalyst(s) to produce hydrogen gas from formic acid solution, or to reduce aldehydes using formic acid, are disclosed and claimed. More specifically, the present invention relates to a group of pentamethylcyclopentadienyl (Cp*) iridium complexes with different Ν,Ν-bidentate ligands that catalyze dehydrogenation from formic acid, and chemo-selective hydrogenation of aldehydes, in the aqueous solution system in a highly efficient, and long life-time manner.

Method for producing 2-halo-6-nitrobenzoic acids

The present invention relates to a process for the preparation of 2-halo-6-nitrobenzoic acids by oxidation of 2-halo-6-nitro-benzyl alcohols, esters, ethers, or mixtures thereof with nitric acid and to the use of this process as a step in the preparation of 2-halo-6-nitrobenzoic acids from 2-halo-6-nitrotoluenes.

Studies on anti-Helicobacter pylori agents. Part 1: Benzyloxyisoquinoline derivatives

The synthesis and optimization of the anti-Helicobacter pylori activity of a novel series of benzyloxyisoquinoline derivatives that was discovered by a random screening process, are described. In the in vitro assay, compound 10c containing a 3-acetamido-2,6-dichlorobenzyl substituent was found to have extremely potent activity against H. pylori and no activity against other common bacteria. The anti-H. pylori activity of 10c was superior to that of amoxicillin (AMPC) (1) and clarithromycin (CAM) (2). However, 10c did not show in vivo efficacy in a mouse infection model; a feature attributed to the lack of strong bactericidal activity at short contact times. (C) 1999 Elsevier Science Ltd.