50907-84-1

Upstream product

• 32754-27-1 methyl 3,5-di-O-benzoyl-β-D-ribofuranoside 
• 5517-61-3 methyl 3'-O-benzoyl-β-D-apiofuranoside 
• 90238-20-3 N,N-diethyl-α,α-difluorobenzylamine 
• 7473-45-2 1-O-methyl-D-ribofuranose 
• 52783-53-6 methyl 2,3,3'-tri-O-benzoyl-β-D-apiofuranoside 
• 98-88-4 benzoyl chloride 

Downstream Products

• 80244-90-2 methyl 2,5-di-O-benzoyl-3-O-m-toluoyl-β-D-ribofuranoside 

Relevant academic research and scientific papers

Selective mono-acylation of 1,2- and 1,3-diols using (α,α- difluoroalkyl)amines

In the reaction of N,N-diethyl-α,α-difluorobenzylamine (DFBA) with 1,2- or 1,3-diols, selective mono-benzoylation occurs to afford mono-esters of the diols in good yield. The reaction is completed under mild conditions in a short reaction time. Further, prim-, sec-, and tert-diols and catechol can be converted to the corresponding mono-benzoates. DFBA is used for the protection of the hydroxy group in sugars. The selective mono-nicotinylation, formylation and pivaloylation of diols are also performed by using the corresponding difluoroalkylamines.

REGIOSELECTIVE O-DEACYLATION OF FULLY ACYLATED GLYCOSIDES AND 1,2-O-ISOPORPYLIDENEALDOFURANOSE DERIVATIVES WITH HYDRAZINE HYDRATE

On hydrazinolyis in 1:4 acetic acid-pyridine, and in pyridine, partisl O-deacylation of fully acylated methyl glycosides and some other glycosyl compounds ( 23 compounds ) was found to be induced, to give, in good yields, products bearing one free hydroxy