5093-32-3

Usage

Uses

2-(4-Bromobutoxy)-1H-isoindole-1,3(2H)-dione is a useful synthesis intermediate.

InChI:InChI=1/C12H12BrNO3/c13-7-3-4-8-17-14-11(15)9-5-1-2-6-10(9)12(14)16/h1-2,5-6H,3-4,7-8H2

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 524-38-9 N-hydroxyphthalimide 
• 85-44-9 phthalic anhydride 

Downstream Products

• 847021-23-2 2-(4-{4-Oxo-2-[(E)-phenylimino]-5-[1-phenyl-meth-(Z)-ylidene]-thiazolidin-3-yl}-butoxy)-isoindole-1,3-dione 
• 847021-03-8 2-(4-{2-[(E)-4-Chloro-phenylimino]-4-oxo-thiazolidin-3-yl}-butoxy)-isoindole-1,3-dione 
• 847021-04-9 2-(4-{2-[(E)-4-Nitro-phenylimino]-4-oxo-thiazolidin-3-yl}-butoxy)-isoindole-1,3-dione 
• 847021-29-8 2-(4-{5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-2-[(E)-phenylimino]-thiazolidin-3-yl}-butoxy)-isoindole-1,3-dione 
• 1152184-51-4 C₂₉H₂₆N₄O₅ 
• 1152184-37-6 C₃₄H₂₈N₆O₅ 
• 1152184-44-5 C₃₁H₂₉N₇O₃ 
• 1197965-77-7 C₂₈H₂₄N₄O₆ 
• 1133387-89-9 C₃₂H₂₅ClN₄O₅S₂ 
• 1133387-85-5 C₃₁H₂₃ClN₄O₄S₂ 
• 1133387-87-7 C₃₁H₂₂Cl₂N₄O₄S₂ 
• 1133387-83-3 C₃₃H₂₈N₄O₅S₂ 
• 1133387-81-1 C₃₂H₂₅ClN₄O₄S₂ 
• 1133387-79-7 C₃₂H₂₆N₄O₄S₂ 

Relevant academic research and scientific papers

5-Formylcytosine Could Be a Semipermanent Base in Specific Genome Sites

5-Formyl-2′-deoxycytosine (fdC) is a recently discovered epigenetic base in the genome of stem cells, with yet unknown functions. Sequencing data show that the base is enriched in CpG islands of promoters and hence likely involved in the regulation of tra

Synthesis and properties of ω-aminooxyalkyliminodiacetic acids, bifunctional chelating agents for carbonyl labeling

3-Aminooxypropyliminodiacetic acid, 4-aminooxybutyliminodiacetic acid and 5-aminooxypentyliminodiacetic acid and their oxime derivatives with several carbonyl compounds were synthesized and characterized. The ω-aminooxyalkyliminodiacetic acids act as bifunctional chelating agents for metal-labeling of a carbonyl group.

Enhancing excess electron transport in DNA

The efficiency of excess electron transport in duplex DNA can be enhanced by limiting the pathways available for migration and using a donor of moderate strength that suppresses radical recombination through selective electron transfer to distal pyrimidines rather than proximal purines.

Synthesis and antibacterial evaluation of some theophylline derivatives

Some novel antiasthmatic theophylline derivatives have been synthesized and evaluated for biological activity. Oxygen substituted hydroxylamine compounds have been found to possess versatile pharmacological activities. Theophylline N-alkoxyarylbiguanides 8a-d have been prepared by condensing corresponding N-alkoxyamine salt 6a-c with substituted aryldicyandiamide 7, which in turn is prepared by Gabriel hydrolysis of corresponding alkoxyphthalimides 5a-c. Theophylline is converted to its sodium salt using sodium hydride and treated with bromoalkoxy phthalimide in DMF media. In an another attempt N-allyl theophylline 9 is brominated and condensed with double mole ratio of N-hydroxyphthalimide to obtain 2,3-bis-oxyphthalimido-1-theophylline propane 11. Majority of these compounds have been screened for their antimicrobial activity.

Synthesis of 3-alkoxy-(substituted aryl) biguanidino-4-methyl-2,3-dihydro (1H)-1,5-benzodiazepine-2-ones and related compounds

Condensation of 3-alkoxyphthalimidopentane 2,4-dione 5a-c, 3-alkoxyaminopentane 2,4-dione salts 7a-c, and 3-alkoxy 5(p-substituted aryl) biguanidinopentane 2,4-diones 10a-o with o-phenylenediamine in xylene gave the corresponding 3-alkoxyphthalimido 2,4-dimethyl (3H) 1,5-benzodiazepines 6a-c, 3-alkoxyamino 2,4-dimethyl (3H) 1,5-benzodiazepines 8a-c, 3-alkoxy (p-substituted aryl) biguanidino 2,4-dimethyl (3H) 1,5-benzodiazepines 11a-c respectively.