50939-39-4 Usage
Uses
Used in Organic Synthesis:
[5-chloro-2-[(2,2,2-trifluoroethyl)amino]phenyl] 2-fluorophenyl ketone is used as an intermediate in organic synthesis for the creation of more complex molecules. Its unique structure and potential reactivity make it a valuable building block for the development of novel compounds with specific properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, [5-chloro-2-[(2,2,2-trifluoroethyl)amino]phenyl] 2-fluorophenyl ketone is used as a key component in the development of new drugs. Its unique structural features may contribute to the design of innovative therapeutic agents, particularly those targeting specific biological pathways or receptors.
Used in Chemical Research:
[5-chloro-2-[(2,2,2-trifluoroethyl)amino]phenyl] 2-fluorophenyl ketone is also utilized in chemical research to study the effects of trifluoromethyl substitution on the properties and reactivity of aromatic ketones. Understanding these effects can lead to the development of new synthetic methods and the discovery of compounds with enhanced performance in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 50939-39-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,9,3 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 50939-39:
(7*5)+(6*0)+(5*9)+(4*3)+(3*9)+(2*3)+(1*9)=134
134 % 10 = 4
So 50939-39-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H10ClF4NO/c16-9-5-6-13(21-8-15(18,19)20)11(7-9)14(22)10-3-1-2-4-12(10)17/h1-7,21H,8H2
50939-39-4Relevant academic research and scientific papers
Yang,Yang
, p. 58 - 63 (1994)
2-Oxoquazepam [7-chloro-1-(N-2,2,2-trifluoroethyl)-5-(2'-fluorophenyl)- 1,3-dihydro-2H-1,4-benzodiazepin-2-one, OQZ], a major pharmacologically active metabolite of quazepam, was hydrolyzed in NaOH solution to form a sodium salt of 2-(N-2,2,2-trifluoroethyl)amino-5-chloro-α-(2'- fluorophenylbenzylidene)glycine. The hydrolysis product was formed via a rapidly established acid-base equilibrium, followed by a rate-determining, ring-opening reaction involving two negatively charged ions. Following neutralization, the hydrolysis product was isolated by reversed-phase HPLC and subsequently identified by its UV-vis absorption and MS analyses. Kinetics of the hydrolysis reaction in acetonitrile/water mixture was studied by reversed-phase HPLC analysis as a function of water content, NaOH concentration, temperature, and ionic strength. In acetonitrile:0.05 N NaOH (1:1, v/v), the hydrolysis of OQZ had an energy of activation of 14.4 kcal/mol and at 25 °C (ΔH((+)) = 13.8 kcal/mol, ΔS((+)) = -31.2 cal/K/mol, and ΔG((+)) = 23.1 kcal/mol).
