50964-16-4Relevant academic research and scientific papers
HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER
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Page/Page column 53-54, (2012/04/23)
An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various disorders is provided. An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells containing a compound represented by the formula (I) (wherein X, Y, Z, Ar1, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof, which can expand hematopoietic stem cells and/or hematopoietic progenitor cells.
A Synthesis of acetamidines
Harjani, Jitendra R.,Liang, Chen,Jessop, Philip G.
experimental part, p. 1683 - 1691 (2011/05/12)
The condensation of primary amine with N,N-dimethylacetamide dimethyl acetal yields amixture of acetamidine and imidate ester. The product distribution in this reaction depends on the temperature, solvent, and structure of the primary amine. It is possible to suppress the formation of imidate ester by performing the reaction in the presence of excess dimethyl amine, yielding acetamidine as the exclusive product. For acetamidines that cannot be purified either by crystallization or distillation, this new method is necessary for the generation of pure acetamidines in good yields.
Synthesis and Enantiomer Recognition of Dipodands and Crown Ethers Containing the 2,3:6,7-Dibenzobicyclonona-2,6-diene Residue as the Chiral Subunit
Naemura, Koichiro,Fukunaga, Rinko,Komatsu, Masanori,Yamanaka, Masatoshi,Chikamatsu, Hiroaki
, p. 83 - 88 (2007/10/02)
Five new optically active crown ethers and six optically active dipodands are reported.The crown ethers were synthesized by using (+)-(1S,4R,5S,8R)-2,3:6,7-dibenzobicyclonona-2,6-diene-4,8-diol and (+)-(1S,4R,5S,8R)-4,8-bis(hydroxymethyl)-2,3:6,7-d
STUDIES ON CYCLOPHOSPHAZENES. II. SYNTHESIS AND CATALYTIC ACTIVITY OF NEW TYPES OF HEXA-SUBSTITUTED CYCLOPHOSPHAZENIC PODANDS
Podda, Gianni
, p. 397 - 400 (2007/10/02)
The reaction between hexakis(p-hydroxybenzyloxy)cyclophosphazene 3 and polyethylene glycol monoalkyl ether tosylate leads to the formation of new types of hexakiscyclophosphazenes.The properties of these derivatives, including their catalytic activity under phase-transfer conditions, have been investigated.
