51-01-4

Usage

Uses

Used in Pain Relief and Fever Reduction:
Aspirin is used as an analgesic and antipyretic agent for the management of mild to moderate pain and fever. It works by inhibiting the production of prostaglandins, which are chemicals responsible for pain, fever, and inflammation.
Used in Cardiovascular Health:
Aspirin is used as an antiplatelet agent to prevent heart attacks and strokes in individuals at high risk. It inhibits platelet aggregation, reducing the risk of blood clot formation and improving blood flow.
Used in Anti-cancer Applications:
Aspirin has been found to possess potential anti-cancer properties, although the exact mechanisms are still under investigation. It may help reduce the risk of certain types of cancer, such as colorectal cancer, by modulating various cellular pathways and processes.
Used in Pharmaceutical Industry:
Aspirin is used as an active pharmaceutical ingredient in various formulations, such as tablets, capsules, and suppositories, for the treatment of pain, fever, inflammation, and cardiovascular conditions.

Upstream product

• 89-86-1 4-hydroxysalicylic acid 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 1222-48-6 7-hydroxy-4'-methoxyflavylium chloride 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 108-46-3 recorcinol 
• 18393-49-2 3',4',7-trihydroxyflavylium chloride 
• 39972-59-3 2,3',4,4'-Tetrahydroxy-chalkon 
• 89494-26-8 2,4-diacetoxy-4'-methoxy-chalcone 
• 2150-11-0 3',4',7-trihydroxyflavone 

Downstream Products

• 91-52-1 2,4 dimethoxybenzoic acid 
• 2237-36-7 4-methoxysalicylic acid 
• 90111-34-5 4-hydroxy-2-methoxybenzoic acid 
• 855875-90-0 3,5-diacetyl-2,4-dihydroxy-benzoic acid 
• 91398-74-2 2-chloro-1-(2,4-diacetoxy-phenyl)-ethanone 
• 861514-29-6 2-acetoxy-4-benzoyloxy-benzoic acid methyl ester 
• 4707-43-1 4-((2,4-dihydroxybenzoyl)oxy)-2-hydroxybenzoic acid 
• 861565-48-2 2-acetoxy-4-(2,4-diacetoxy-benzoyloxy)-benzoic acid 

Relevant academic research and scientific papers

Improved compsn. antiallergic habitus

PROBLEM TO BE SOLVED: To provide a composition for ameliorating allergic constitution naturally ingestible in daily life. SOLUTION: The composition for ameliorating the allergic constitution comprises a galactooligosaccharide as a main ingredient. Furthermore, a food and drink uses the composition. Since the galactooligosaccharide is already widely used in heath-oriented foods such as a specific food for health and is a material in which the safety is sufficiently established, the galactooligosaccharide is naturally ingestible over a long period in the daily life. COPYRIGHT: (C)2007,JPOandINPIT

Synergistic compositions for the selective control of tumor tissue

According to the invention, compositions are made available which have a strong cytotoxic effect which is largely selective on tumor tissue. The invention is based on the fact that certain benzoic acid derivatives have a strong synergistic effect as a mixture and destroy cancer cells selectively in a pH range of 7 or below, such as from 6.5 to 7.

Synergistically acting compositions for selectively combating tumor tissue

According to the invention, compositions are made available which have a strong cytotoxic effect which is largely selective on tumor tissue. The invention is based on the fact that certain benzoic acid derivatives have a strong synergistic effect as a mixture and destroy cancer cells selectively in a pH range of 7 or below, such as from 6.5 to 7.

Medicaments for the selective treatment of tumor tissues

Medicinal products for the selective control of tumor tissue and a method for control of such tumor tissue by administration of such product to a host. The products comprise: (a) two different compounds having a pH below 7 when the compounds are present i

Cobalt(II)-Catalyzed Reaction of Aldehydes with Acetic Anhydride under an Oxygen Atmosphere: Scope and Mechanism

The reaction of aldehydes with acetic anhydride in the presence of catalytic cobalt(II) chloride under an oxygen atmosphere at ambient temperature is dependent upon the reaction medium.Aliphatic aldehydes react in acetonitrile to give 1,2-diones whereas the aromatic aldehydes are acylated to yield the corresponding acylals.On the other hand, carboxylic acids are obtained from aliphatic and aromatic aldehydes by conducting the reaction in dichloroethane or benzene.Cobalt(II) chloride in acetonitrile catalyzes the conversion of aliphatic aldehydes to the correspondinganhydrides in the absence of acetic anhydride whereas aromatic aldehydes remain largely unaffected under these conditions.A preliminary mechanistic study in three different solvents (i.e. acetonitrile, dichloroethane, and DMF) has revealed that in acetonitrile and in the presence of acetic anhydride, aliphatic aldehydes behave differently than aromatic aldehydes.Some trapping experiments using methyl acrylate and stilbene have been conducted to demonstrate the occurence of an acyl cobalt and peroxyacyl cobalt intermediate during these reactions.

Cobalt (II) catalyzed oxidation of aldehydes to carboxylic acid with molecular oxygen

A variety of aromatic and some aliphatic aldehydes are efficiently transformed to the corresponding carboxylic acid in presence of catalytic amount of Cobalt (II) chloride, molecular oxygen and acetic anhydride at room temperature. Phenolic aldehydes undergo acylative oxidation to give the corresponding acylated carboxylic acid.

A New Method for the Degradation of Anthocyanidins, Flavones, Chalcones, and Coumarins

After transformation into the corresponding chalcone or flavenol acetates anthocyanidins are oxidatively cleaved with ruthenium tetroxide to yield benzoic acid derivatives of the rings A and B.Flavones, chalcones, and coumarins are degradated by the same method.