510-66-7 Usage
General Description
(4aS,7aR)-3,4,6,7,7a,8-Hexahydro-12-hydroxy-11-methoxy-7-methyldibenz[d,f]indol-2(5H)-one is a chemical compound with a complex molecular structure. It belongs to the class of dibenzindolones and has a hexahydro-12-hydroxy-11-methoxy-7-methyl moiety. (4aS,7aR)-3,4,6,7,7a,8-Hexahydro-12-hydroxy-11-methoxy-7-methyldibenz[d,f]indol-2(5H)-one is a derivative of the alkaloid biogen. Its structure includes a dibenzindolone core with a hydroxyl group and a methoxy group attached to it. (4aS,7aR)-3,4,6,7,7a,8-Hexahydro-12-hydroxy-11-methoxy-7-methyldibenz[d,f]indol-2(5H)-one may have potential pharmacological or biological activities due to its unique structure, and further research may be needed to understand its potential uses and effects in different applications.
Check Digit Verification of cas no
The CAS Registry Mumber 510-66-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 510-66:
(5*5)+(4*1)+(3*0)+(2*6)+(1*6)=47
47 % 10 = 7
So 510-66-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO3/c1-19-8-7-18-6-5-12(20)10-13(18)16-11(9-15(18)19)3-4-14(22-2)17(16)21/h3-4,10,15,21H,5-9H2,1-2H3
510-66-7Relevant articles and documents
One-pot conversion of thebaine to hydrocodone and synthesis of neopinone ketal
Carroll, Robert J.,Leisch, Hannes,Rochon, Lena,Hudlicky, Tomas,Cox, D. Phillip
experimental part, p. 747 - 752 (2009/07/25)
The ethylene glycol ketal of neopinone was prepared in a one-pot procedure by the reaction of thebaine with ethylene glyocol in the presence of p-toluenesulfonic acid. The ketal is also an intermediate in the conversion of thebaine to hydrocodone with ethylene glycol and Pd(OAc)2, followed by hydrogenation. Additionally, a one-pot procedure for the conversion of thebaine to hydrocodone was achieved by employing palladium catalysis in aqueous medium. Palladium serves a dual purpose in this transformation, first for the activation of the dienol ether of thebaine and second as a hydrogenation catalyst. This procedure was found to be comparable to the two-step protocol which employs diimide reduction of thebaine followed by acid-catalyzed hydrolysis of the resulting 8,14-dihydrothebaine to hydrocodone. Experimental and spectral data are provided for all compounds.
