51006-03-2Relevant academic research and scientific papers
Formation of novel thiazolomorphinans and thiazoloaporphines
Girán, Levente,Berényi, Sándor,Sipos, Attila
, p. 10388 - 10394 (2008)
A novel strategy has been developed for the synthesis of ring A fused thiazolomorphinans and ring D fused thiazoloaporphines offering the possibility of formation of regioisomeric products. The conventional thermal thiazole-forming reaction was replaced with microwave initiation and a detailed discussion has been presented on the proposed mechanism of the ring closure.
Synthesis of morphinans with diversely functionalized benzoxazole moieties
Giran, Levente,Gyulai, Zsuzsanna,Antus, Sandor,Berenyi, Sandor,Sipos, Attila
, p. 1135 - 1143 (2010)
Three independent strategies have been established for the synthesis of morphinans with oxazole moieties derived from the aminophenol function of 2-aminomorphine. All the procedures possess the ability to furnish diversely substituted 2′-oxazole moieties
