51010-74-3

Basic information

• Product Name: MORPHOLINOSULFUR TRIFLUORIDE
• Synonyms: MORPHOLINOSULPHUR TRIFLUORIDE (MORPHO DAST);Morph-DAST, Morpho-DAST;4-Morpholinylsulfur trifluoride, 95%;Morpholin-4-ylsulphur trifluoride;Morpho-DAST, 4-(Trifluorothio)morpholine;4-(trifluoro-$l^{4}-sulfanyl)morpholine;MORPHOLINOSULFUR TRIFLUORIDE;MORPHOLINOSULPHUR TRIFLUORIDE
• CAS NO: 51010-74-3
• Molecular Formula: C₄H₈F₃NOS
• Molecular Weight: 175.17
• EINECS: -0
• Mol File: 51010-74-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 175 °C (decomp)
• Boiling Point: 41-42 °C0.5 mm Hg(lit.)
• Flash Point: 169 °F
• Appearance: clear yellow to amber liquid
• Density: 1.436 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.155mmHg at 25°C
• Refractive Index: n20/D 1.454(lit.)
• Storage Temp.: 2-8°C
• PKA: -7.46±0.20(Predicted)
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 606224
• CAS DataBase Reference: MORPHOLINOSULFUR TRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: MORPHOLINOSULFUR TRIFLUORIDE(51010-74-3)
• EPA Substance Registry System: MORPHOLINOSULFUR TRIFLUORIDE(51010-74-3)

Safety Data

• Hazard Codes: C,E
• Statements: 14-34-5
• Safety Statements: 26-36/37/39-45-27-8
• RIDADR: UN 3265 8/PG 1
• WGK Germany: 3
• F: 10-21
• HazardClass: 8
• PackingGroup: I
• Hazardous Substances Data: 51010-74-3(Hazardous Substances Data)

Usage

Uses

4-Morpholinylsulfur trifluoride is incorporated in the fluoronation of trihexanols. It is used as a nucleophilic fluorinating agent with greater thermal stability. It is also used in the preparation of proline analogs and in the preparation of difluoropiperidines.

InChI:InChI=1/C9H3F6N/c10-8(11,12)6-1-2-7(9(13,14)15)5(3-6)4-16/h1-3H

Upstream product

• 103-34-4 4,4'-dithiodimorpholine 

Downstream Products

• 16066-32-3 4-(benzenesulfinyl)morpholine 

Relevant articles and documents

A new method for the synthesis of organosulfur trifluorides

Simple, convenient and universal method of the different types of organosulfur trifluorides synthesis, with common formula RSF3 where R = dialkylamino group, aromatic or heterocyclic radical, was elaborated. The method consists in the reaction of thiosulf