51012-35-2

Upstream product

• 644-34-8 (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-phenylprop-2-en-1-one 
• 106-65-0 Dimethyl succinate 

Downstream Products

• 79510-76-2 2-[(Z)-3-Benzo[1,3]dioxol-5-yl-1-phenyl-prop-2-en-(Z)-ylidene]-succinic acid 
• 79510-77-3 2-(3-Benzo[1,3]dioxol-5-yl-1,2,3-tribromo-1-phenyl-propyl)-2-bromo-succinic acid 1-methyl ester 
• 79510-84-2 3-Acetoxy-4-(benzo[1,3]dioxol-5-yl-bromo-methyl)-1,4,5-tribromo-5-phenyl-cyclopent-2-enecarboxylic acid methyl ester 
• 79510-82-0 C₂₇H₂₀N₂O₆ 
• 79510-78-4 2-(3-Benzo[1,3]dioxol-5-yl-1,2,3-tribromo-1-phenyl-propyl)-2-bromo-succinic acid 
• 79510-85-3 3-[1-Benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-4-hydroxy-2-phenyl-cyclopenta-1,4-dienecarboxylic acid hydrazide 
• 79510-81-9 {4-Benzo[1,3]dioxol-5-yl-5-[(E)-hydroxyimino]-2-phenyl-cyclopenta-1,3-dienyl}-acetic acid 
• 79510-80-8 3-phenyl-5-piperonylcyclopentadien-1-one-2-acetic acid 
• 79510-83-1 methyl 5-acetoxy-2-phenyl-1-piperonylcyclopentadiene-3-carboxylate 

Relevant academic research and scientific papers

Stobbe Condensation with Piperonylideneacetophenone: Part V - Synthesis and Biological Screening of Some New Cyclopentadienes and Cyclopentadienones

Piperonylideneacetophenone undergoes condensation with excess dimethyl succinate in the presence of potassium t-butoxide to give acid ester (Ia) in addition to an unidentified product.The acid ester Ia is converted into cyclopentadiene (IV) and cyclopentadienone (III) derivatives via two different routes.All the compounds have been tested in vitro for their antimicrobial activity against a number of gram -ve and gram +ve bacteria.