51030-44-5

Usage

Uses

Used in Pharmaceutical Industry:
2-Benzyloxycarbonylamino-acetimidic acid ethyl ester, hydrochloride is used as a key intermediate in the synthesis of various drugs for its ability to modulate biological processes. It contributes to the development of new pharmaceuticals by facilitating the creation of complex molecular structures that can target specific biological pathways.
Used in Chemical Reactions:
In the field of organic chemistry, 2-Benzyloxycarbonylamino-acetimidic acid ethyl ester, hydrochloride is used as a protecting group for amino acids. This application is crucial for preventing unwanted side reactions during the synthesis of peptides and other biologically active compounds, ensuring the desired product is obtained with high purity and yield.
Used in Peptide Synthesis:
2-Benzyloxycarbonylamino-acetimidic acid ethyl ester, hydrochloride plays a significant role in peptide synthesis, where it is employed to protect the amino group of amino acids during the formation of peptide bonds. This protection allows for the stepwise assembly of peptide chains with precise control over the sequence and structure, leading to the production of biologically active peptides with specific functions.

InChI:InChI=1/C12H16N2O3/c1-2-16-11(13)8-14-12(15)17-9-10-6-4-3-5-7-10/h3-7,13H,2,8-9H2,1H3,(H,14,15)

Upstream product

• 3589-41-1 phenylmethyl cyanomethylcarbamate 
• 501-53-1 benzyl chloroformate 
• 6011-14-9 2-aminoacetonitrile hydrochloride 
• 75-36-5 acetyl chloride 

Downstream Products

• 60603-42-1 (1H-benzoimidazol-2-ylmethyl)-carbamic acid benzyl ester 
• 4511-71-1 2-Amino-2'-(benzyloxy-carbonyl-glycyl-amino)-biphenyl 
• 5816-56-8 N--N'--hydrazin 
• 5816-55-7 N--N'--hydrazin 
• 101742-62-5 N',N'-Dimethyl-benzyloxycarbonylamino-acetamidin 
• 63808-38-8 Z-ImGly-Gly-OH 
• 101594-09-6 N'-Methyl-benzyloxycarbonylamino-acetamidin 
• 76055-02-2 2-benzyloxycarbonylamino-N-(2-pyridyl)acetamidine hydrochloride 
• 144397-27-3 ((4R,5S)-4-Methyl-5-phenyl-4,5-dihydro-oxazol-2-ylmethyl)-carbamic acid benzyl ester 
• 83520-08-5 2-Benzyloxycarbonylamino-N-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-acetimidic acid ethyl ester 
• 64194-97-4 3-(acetylamino)-2-<<(benzyloxycarbonyl)amino>methyl>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxyquinazoline 
• 94711-39-4 N-(Benzyloxycarbonylamino-acetimidoyl)-N'-benzoyl-hydrazin 
• 50850-21-0 (2-Amino-3,3-dicyano-allyl)-carbamic acid benzyl ester 
• 884335-30-2 N¹-Boc-N⁵-(1-imino-2-(N-benzyloxycarbonyl)aminoethyl)-L-ornithine 

Relevant academic research and scientific papers

The synthesis of unusual tetrahydropyrimidine amino acids

The synthesis of derivatives of 2-(1-an-aminoalkyl)-4-carboxy-3,4,5,6-tetrahydropyrimidines, unusual amino acids isolated from bacterial siderophores, is described, from condensation of N-protected amino acids imidates or thiomidates with 2,4-diaminobutyrylglycine methyl ester.

Purines, Pyrimidines, and Imidazoles. Part 54. Interconversion of Some Intermediates in the de novo Biosynthesis of Purine Nucleotides

Ethyl and benzyl 5-amino-1-(2-pyridyl)imidazole-4-carboxylates, obtained from ethyl or benzyl α-amino-α-cyanoacetate, respectively, and ethyl formimidate hydrochloride followed by 2-aminopyridine, were converted into 5-amino-1-(2-pyridyl)imidazole-4-carboxylic acid which was decarboxylated in situ to 5-amino-1-(2-pyridyl)imidazole.Reaction of 2-N-formylamino-N-(2-pyridyl)acetamide with ammonia and ammonium chloride gave 5-aminoimidazole and a similar reaction with the nucleotide 2-N-formylglicineamide ribotide similarly gave evidence for aminoimidazole formation. 4-Cyano-5- imidazolone, prepared by reaction of 2-cyano-N-formylacetamide with nitrous acid and reduction of the hydroxyimino derivative so produced, with ammonia and ammonium sulphite at 100 deg C, gave 5-aminoimidazole-4-carboxamide.Implications of the reactions involved are discussed.