51034-71-0Relevant academic research and scientific papers
Synthesis and reactivity of cross-conjugated polyenones with a planar chirality
Marchand, Nathalie J.,Gree, Danielle M.,Martelli, Jacques T.,Gree, Rene L.,Toupet, Loic J.
, p. 5063 - 5072 (1996)
The complexes 6 are the first examples of a novel class of cross conjugated polyenones bearing a planar chirality introduced by an organometallic moiety. Their synthesis is described using, as a key intermediate, the easily accessible new phosphorane 9. The free double bond of the selectively protected polyenes 6 reacts efficiently, although with low diastereoselectivities, in Diels-Alder or 1,3 dipolar cycloaddition reactions or with nucleophiles. Cyclopentyl radical also adds to 6, and this is the first example of a radical reaction in the presence of carbonyliron complexes. Decomplexation of the various adducts leads, in good yields, to the corresponding polyfunctionalized free dienes, which can be of further synthetic use.
Primary Kinetic Isotope Effects in Hydride Transfer: Experimental Studies of Intramolecular Hydride Migration and ab initio Molecular Orbital Calculations of Model Systems.
Hillier, Ian H.,Smith, Stephen,Mason, Stephen C.,Whittleton, Stephen N.,Watt, C. Ian F.,Willis, Julie
, p. 1345 - 1352 (2007/10/02)
Measurements of the primary kinetic hydrogen isotope effects for the intramolecular migration of hydride accompanying the rearrangements of (i) hydroxy-ketones involving 1,4-migration of hydride between ketonic carbonyl groups and (ii) phenylglyoxal hydrates to their corresponding mandelic acids are described.The results are discussed using ab initio MO calculations od model systems, with a variety of basis sets.The value of such model calculations is demonstrated.
