51040-49-4

Upstream product

• 138234-43-2 (+/-)-Methyl 3-<(4-chlorophenyl)sulfinyl>propanoate 
• 536-74-3 phenylacetylene 
• 54696-23-0 Methyl 3-<(4-chlorophenyl)sulfenyl>propanoate 
• 106-54-7 p-Chlorothiophenol 
• 85143-08-4 5-(4-Chloro-phenylsulfanyl)-4-phenyl-[1,2,3]selenadiazole 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 33440-88-9 silver phenylacetylide 
• 1679-18-1 4-Chlorophenylboronic acid 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 85143-22-2 C₁₅H₁₄ClN₃OS 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 

Downstream Products

• 92150-69-1 1-chloro-4-((phenylethynyl)sulfonyl)benzene 

Relevant academic research and scientific papers

Transition Metal-Free C-H Thiolation via Sulfonium Salts Using β-Sulfinylesters as the Sulfur Source

We disclose a direct C(sp)-, C(sp2)-, and C(sp3)-H thiolation reaction using β-sulfinylesters as the versatile sulfur source. The key step of this protocol is chemoselective C-S bond cleavage of the sulfonium salts that are formed in situ from the corresponding alkenes, alkynes, and 1,3-dicarboxyl compounds with β-sulfinylesters. The successful capture of the acrylate byproduct supports a retro-Michael reaction mechanism.

Ru-Catalyzed [3 + 2] Cycloaddition of Nitrile Oxides and Electron-Rich Alkynes with Reversed Regioselectivity

Polarity reversal ("umpolung") of a functional group can override its inherent reactivity and lead to distinct bond-forming modes. Herein we describe a rarely studied cycloaddition between nitrile oxides and electron-rich alkynes with reversed regioselect

Radical-mediated sulfonyl alkynylation, allylation, and cyanation of propellane

Bicyclo[1.1.1]pentane (BCP) is widely applied as the bioisostere for aryl, internal alkynes, andtert-butyl groups in medicinal chemistry. We herein disclose an efficient and practical preparation of sulfonyl alkynyl/allyl/cyano-substituted BCP derivatives

Highly dispersed Ni2P nanoparticles on N,P-codoped carbon for efficient cross-dehydrogenative coupling to access alkynyl thioethers

An ultrafine Ni2P (a metal-rich interstitial phosphide compound) nanoparticles with a narrow size distribution homogeneously dispersed on N,P-codoped carbon was developed for efficient synthesis of alkynyl thioethers via base- and ligand-free cross-dehydrogenative coupling (CDC) of terminal alkynes and thiols using atmospheric air as the oxidant under mild conditions. A remarkable catalytic performance with good functional group compatibility, broad substrate scope and high stability is accomplished. Pyridinic N atoms are identified as basic sites for facilitating the activation of terminal alkynes via hydrogen bonding interactions and play a key role in the success of this base- and ligand-free CDC reaction.

N-Alkynylthio Phthalimide: A Shelf-Stable Alkynylthio Transfer Reagent for the Synthesis of Alkynyl Thioethers

A new kind of electrophilic alkynylthiolating reagent, called N-alkynylthio phthalimide, is designed and synthesized herein. This electrophilic sulfenylating reagent can be easily prepared in three steps from commercially available phthalimide and corresp

Hollow nanoshell-sphere Fe@Fe/Pd reactors: a magnetically recoverable catalyst for the Csp–S cross-coupling reactions in water

The hollow Pd–PVP–Fe nanosphere and Fe–PVP nanoparticle catalysts were synthesized by thermal method. Mixing of two metallic nanocatalysts was applied in the Csp–S cross-coupling reactions between diphenyl disulfide and phenylacetylene under mi

A heterogeneous copper(I)-catalyzed aerobic oxidative cross-dehydrogenative coupling of terminal alkynes with thiols leading to alkynyl sulfides

A heterogeneous copper-catalyzed direct oxidative cross-dehydrogenative coupling of terminal alkynes with thiols was achieved in DMSO at 70 °C in the presence of an MCM-41-supported bidentate nitrogen copper(I) complex [MCM-41-2N-CuCl] and K2CO

Cu(i)-catalyzed aerobic cross-dehydrogenative coupling of terminal alkynes with thiols for the construction of alkynyl sulfides

Highly active and selective aerobic cross-dehydrogenative coupling of terminal alkynes with thiols to construct alkynyl sulfides catalyzed by Cu(i) using molecular oxygen as the oxidant has been demonstrated under mild reaction conditions. The process is applicable to a wide range of alkynes and various thiols and is compatible with a variety of functional groups on both alkyne and thiol coupling partners.

Selenium Heterocycles. XXXV. Synthesis and Pyrolysis of Aryloxy-, Arylthio-, and Arylseleno-1,2,3-selenadiazoles

A series of 4-substituted-5-arylthio-1,2,3-selenadiazoles, 4-substituted-5-arylseleno-1,2,3-selenadiazoles and 4-aryloxymethyl-1,2,3-selenadiazoles were synthesized.Pyrolysis of these compounds afforded the corresponding acetylenes XI, XIII (X = S, Se) and XII, respectively.Oxidation of 4-substituted-5-arylthio-1,2,3-selenadiazoles (XIV) with m-chloroperbenzoic acid gave 4-substituted-5-arylsulfinyl-1,2,3-selenadiazoles (XV) and 4-substituted-5-arylsulfonyl-1,2,3-selenadiazoles (XVI).