51063-99-1

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL(R)(+)-2-BROMO-PROPANOATE is used as a reagent in the pharmaceutical industry for the synthesis of various pharmaceuticals. Its unique properties make it a valuable component in the development of new drugs and medications.
Used as a Chemical Intermediate:
In the field of organic chemistry, ETHYL(R)(+)-2-BROMO-PROPANOATE serves as a chemical intermediate. It plays a crucial role in the production of other organic compounds, contributing to the synthesis of a wide range of chemical products.

Upstream product

• 60-29-7 diethyl ether 
• 57057-80-4 ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate 
• 925-90-6 ethylmagnesium bromide 
• 108-91-8 cyclohexylamine 
• 535-11-5 Ethyl 2-bromopropionate 
• 100-46-9 benzylamine 
• 205517-34-6 (3S)-N,N'-bis-(p-methoxybenzyl)-3-isopropyl-piperazine-2,5-dione 

Downstream Products

• 127306-59-6 (-)-(S)-Ethyl-2-fluorpropionat 
• 128023-47-2 ethyl (S)-2-<4-<(1,4-dioxaspiro<4,5>dec-6-yl)methyl>phenoxy>-propanoate 
• 68048-45-3 (S)-(-)-2-(2-methoxy-4-hydroxymethylphenoxy)propionic acid 
• 76671-57-3 (S)-(?)-ethyl 2-phenoxypropionate 
• 220910-26-9 (S)-N-<2-(3-chlorobenzamino)ethyl>alanine ethyl ester 
• 338-69-2 D-Alanine 
• 39922-60-6 ethyl 2-(1-hydroxycyclohexyl)propionate 
• 105528-61-8 benzyl 2-acetamido-4,6-O-benzylidene-2,3-dideoxy-3-<amino>-α-D-glucopyranoside 
• 105528-61-8 benzyl 2-acetamido-4,6-O-benzylidene-2,3-dideoxy-3-<amino>-α-D-glucopyranoside 

Relevant academic research and scientific papers

Enantiodiscrimination of racemic electrophiles by diketopiperazine enolates: asymmetric synthesis of methyl 2-amino-3-aryl-butanoates and 3-methyl-aspartates

Enolates of (S)-N,N′-bis-(p-methoxybenzyl)-3-iso-propylpiperazine-2,5-dione exhibit high levels of enantiodiscrimination in alkylations with (RS)-1-aryl-1-bromoethanes and (RS)-2-bromoesters, affording substituted diketopiperazines containing two new stereogenic centres in high de. Deprotection and hydrolysis of the resultant substituted diketopiperazines provides a route to the asymmetric synthesis of homochiral methyl 2-amino-3-aryl-butanoates and 3-methyl-aspartates in high de and ee.

Lipase catalysed synthesis of optically enriched α-haloamides

An efficient lipase catalysed synthesis of optically enriched α-halogenated amides with concomitant optical enrichment of the starting α-haloesters is described. Candida antarctica lipase (CAL) was found to be a better catalyst over porcine pancreatic lipase (PPL) and Candida cylindracea lipase (CCL). The effect of different organic solvents was also studied.