510712-93-3Relevant academic research and scientific papers
One-pot synthesis of benzoquinoline and coumarin derivatives using Meldrum's acid in three-component reactions
Wang, Xue-Mei,Ye, He-Lin,Qaun, Zheng-Jun,Wang, Xi-Cun
, p. 2357 - 2367 (2013)
A series of 1-aryl-1,2-dihydrobenzo[f]quinolin-3(4H)-one derivatives and 4-aryl-7,7-dimethyl-5-oxo-3,4,5,6,7,8-hexahydrocoumarin derivatives have been synthesized by one-pot multicomponent reaction of Meldrum's acid with benzaldehyde, naphthalene-2-amine, or cyclohexanedione in PEG-400. The method has the advantages of mild reaction conditions, good yields, and easy processing, and is environmentally benign.
Three component one-pot synthesis of 1-aryl-4-benzo[f]quinoline derivatives in glycerol
Wang, Xue-Mei,Ma, Xin,Ma, Hai-Long
, p. 1053 - 1055 (2015/02/05)
A series of 1-aryl-1,2-dihydrobenzo[f]quinolin-3(4H)one derivatives were synthesized by one-pot muticomponent reaction of Meldrum's acid with benzaldehyde, naphthalene-2-amine in glycerol. Glycerol, a new green organic solvent, it not only acts as a catalyst but also as a recyclable solvent by significantly enhancing the intramolecular cyclization. When compared with classical methods, this method has the advantages of milder reaction conditions, good yields, easy processing and environmental benignity. All compounds were characterized by elemental analysis, FT-IR and 1H NMR spectra.
