510730-66-2Relevant academic research and scientific papers
Synthesis of chiral α-amino acids
Chakraborty, Tushar K.,Ghosh, Animesh
, p. 9691 - 9693 (2007/10/03)
A novel method for the synthesis of chiral α-amino acids has been developed where the acid functionality was constructed by oxidizing a hydroxymethyl group introduced by Evans' method in the α-position of an appropriate acid substrate and the amino part came from the amide of the original carboxyl group following a modified Hofmann rearrangement reaction.
