67862-09-3Relevant academic research and scientific papers
Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion
Mori, Tomonori,Miyagi, Marie,Suzuki, Kengo,Shibasaki, Mitsuhito,Saikawa, Yoko,Nakata, Masaya
, p. 275 - 291 (2008/03/12)
The cyclic peptide portion of chlorofusin was synthesized by condensation of the five segments, d-Ada-OTMSE, Boc-l.-Orn(Cbz), Boc-l-Thr-l-Ala, l-Asn(Tr)-d-Asn(Tr)-d-Leu-OTMSE, and Boc-l-Thr-d-Leu, followed by cyclization at the amide bond between d-Ada an
Synthesis of chiral α-amino acids
Chakraborty, Tushar K.,Ghosh, Animesh
, p. 9691 - 9693 (2007/10/03)
A novel method for the synthesis of chiral α-amino acids has been developed where the acid functionality was constructed by oxidizing a hydroxymethyl group introduced by Evans' method in the α-position of an appropriate acid substrate and the amino part came from the amide of the original carboxyl group following a modified Hofmann rearrangement reaction.
