510774-07-9

Upstream product

• 98837-36-6 methyl 3-hydroxy-2-methylenebutyrate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 50-00-0 formaldehyd 
• 510774-06-8 (3-(bromomethyl)but-3-en-2-yloxy)(tert-butyl)diphenylsilane 

Downstream Products

• 916461-60-4 (6E,8E)-1-(tert-butyldiphenylsilyloxy)-4,6,8,10,10-pentamethyl-3-methyleneundeca-6,8-dien-5-one 
• 916461-39-7 anti-(4R,5R,6E,8E)-1-(tert-butyldiphenylsilyloxy)-4,6,8,10,10-pentamethyl-3-methyleneundeca-6,8-dien-5-ol 
• 510774-04-6 (4-bromo-3-methylenepentyloxy)(tert-butyl)diphenylsilane 

Relevant academic research and scientific papers

Total synthesis of antillatoxin

The total synthesis of natural (4R,5R)-antillatoxin and its analog (4S,5S)-antillatoxin has been achieved; the optically pure key intermediates were prepared from indium mediated allylation of either primary or secondary allylic bromide with aldehyde in a

Studies towards total synthesis of antillatoxin: Indium-mediated allylation reaction of carbonyl compounds with secondary allylic bromide in aqueos media

We have established a new reaction condition for the indium-mediated allylation of an unreactive secondary allylic bromide with aldehydes in aqueous media to afford the corresponding homoallylic alcohols in high yields and syn diastereoselectivity. Furthe