51086-08-9

Usage

InChI:InChI=1/C11H11NO/c1-2-7-13-10-3-4-11-9(8-10)5-6-12-11/h2-6,8,12H,1,7H2

Upstream product

• 1953-54-4 indol-5-ol 
• 106-95-6 allyl bromide 
• 2581-34-2 3-methyl-4-nitrophenol 
• 120106-18-5 4-(allyloxy)-2-methyl-1-nitrobenzene 
• 556-56-9 allyl iodid 

Downstream Products

• 1092837-34-7 5-(allyloxy)-1-tosyl-1H-indole 
• 1386456-34-3 5-allyloxy-1H-indole-3-carbaldehyde 
• 710982-56-2 5-allyloxy-1-benzenesulfonyl-1H-indole 
• 132560-38-4 1-benzoyl-4-(2'-di-n-propylaminoethyl)-5-methoxy-2,3-dihydroindole 
• 132560-37-3 1-benzoyl-5-methoxy-2,3-dihydroindole-4-acetaldehyde 
• 132560-36-2 4-allyl-1-benzoyl-5-methoxy-2,3-dihydroindole 

Relevant academic research and scientific papers

Synthesis of a dihydropyrano[3,2-e]indole as a rotationally restricted phenolic analog of the neurotransmitter serotonin

1-(2-Dimethylaminoethyl)-8,9-dihydropyrano[3,2-e]indole has been synthesized via a six step procedure involving a Claisen rearrangement of a 5-allyloxyindole-3-glyoxamide. This novel heterocycle (1) represents a rotationally restricted phenolic analog of the neurotransmitter [3-(2-aminoethyl)-5-hydroxyindole].

INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD)

The present invention provides a compound of formula (I): a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Total synthesis of (-)-serotobenine

The efficient total synthesis of (?)-serotobenine (1) has been achieved by constructing an optically active dihydrobenzofuran ring via a rhodium carbenoid mediated intramolecular C?H insertion reaction, which was developed by our group. Then the possibili

ARYL, ARYLOXY, AND ALKYLOXY SUBSTITUTED 1H-INDOL-3-YL GLYOXYLIC ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1)

Compounds of formula (I) are provided: wherein R1, R2 and R3, are as defined herein, as well ad pharmaceutical composition and methods using the compounds as inhibitors of plasminogen activator inhibitor (PAI-1) and as the

Antidiabetic agents

The instant invention is concerned with aryl and heteroaryl oxyacetic acid type compounds which are useful antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and related diseases and for lowering triglyceride levels are also disclosed.

Antidiabetic agents

The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.

The synthesis of pyrano[3,2-e]indoles and pyrano[2,3-f]indoles as rotationally restricted phenolic analogs of the neurotransmitter serotonin

The synthesis of two rotationally restricted phenolic analogs (1a and 1b) of the neurotransmitter serotonin have been accomplished. The syntheses of 8,9-dihydropyrano[3,2-e]indole (13a) and 7,8-dihydropyrano[2,3-f]indole (13b), which formed the template f

CHEMISTRY OF 6H-PYRIDOCARBAZOLES. PART 13. SYNTHESES OF RING-A- AND RING-D-SUBSTITUTED ELLIPTICINES

The syntheis of 3-hydroxymethyl-5,11-dimethyl-6H-pyridocarbazole is described, and uses a modified Cranwell-Saxton approach to ellipticines.The rearrangement of 9-allyl-6-methoxy-1,4-dimethylcarbazole to the 8-allyl isomer has been employed as the