511-45-5

Basic information

• Product Name: pridinol
• Synonyms: pridinol;1,1-Diphenyl-3-piperidino-1-propanol;Diphepanol;C-238;HH-212;Nonplesin;Ridinol;α,α-Diphenyl-1-piperidine-1-propanol
• CAS NO: 511-45-5
• Molecular Formula: C₂₀H₂₅NO
• Molecular Weight: 295.4186
• EINECS: 208-128-0
• Mol File: 511-45-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 120-121°
• Boiling Point: 460.9 °C at 760 mmHg
• Flash Point: 229.9 °C
• Appearance: /
• Density: 1.079 g/cm³
• Vapor Pressure: 2.71E-09mmHg at 25°C
• PKA: 13.49±0.29(Predicted)
• CAS DataBase Reference: pridinol(CAS DataBase Reference)
• NIST Chemistry Reference: pridinol(511-45-5)
• EPA Substance Registry System: pridinol(511-45-5)

Safety Data

• Hazardous Substances Data: 511-45-5(Hazardous Substances Data)

Usage

Definition

ChEBI: A piperidine substituted at position 1 by a 3-hydroxy-3,3-diphenylpropyl group.

InChI:InChI=1/C20H25NO.CH4O3S/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;1-5(2,3)4/h1-2,4-7,10-13,22H,3,8-9,14-17H2;1H3,(H,2,3,4)

Upstream product

• 73-63-2 1-phenyl-3-(piperidin-1-yl)propan-1-one 
• 110-89-4 piperidine 
• 23573-93-5 methyl 3-(piperidino)propionate 
• 100-58-3 phenylmagnesium bromide 
• 13961-05-2 1,1-diphenyl-1,3-propanediol 
• 1932-03-2 2-(piperidin-4-yl)ethyl chloride 
• 119-61-9 benzophenone 
• 405212-52-4 N-methoxy-N-methyl-3-(piperidine-1-yl)propanamide 
• 59629-70-8 butyl 3-(piperidin-1-yl)propanoate 
• 19653-33-9 ethyl piperidine-1-propionate 

Downstream Products

• 6856-31-1 pridinol methanesulfonate 
• 29869-50-9 1-(3-cyclohexyl-3-phenyl-propyl)-piperidine 
• 67562-42-9 1-(3ξ-cyclohexyl-3ξ-phenyl-allyl)-piperidine 
• 144-11-6 trihexyphenidyl 
• 13150-57-7 1,1-Diphenyl-3-piperidino-1-propene 
• 112971-92-3 Dicyclidol 
• 112866-52-1 Piridinol-methoiodid 
• 114036-17-8 1-ethyl-1-(3-hydroxy-3,3-diphenyl-propyl)-piperidinium; iodide 

Relevant articles and documents

A methanesulfonic acid pu vertical preparation method

The invention discloses a preparation method of pridinol mesylate. The preparation method comprises the following steps: carrying out reaction on methyl acrylate and piperidine to obtain methyl 3-(1-piperidyl) propionate, carrying out reaction on methyl 3-(1-piperidyl) propionate and phenyl magnesium bromide (as a Grignard reagent) to obtain pridinol, and forming a salt by pridinol and methanesulfonic acid in a solvent such as an ether solvent to obtain pridinol mesylate as a final product. The process route is simple in synthetic steps, is short in reaction route, is high in yield and is economical and practical.

Tuning the reducing properties of 1,2-diaryl-1,2-disodiumethanes

(Chemical Equation Presented) We investigated the reducing properties of a series of 1,2-diaryl-1,2-disodiumethanes by means of equilibration reactions. The electron-donor power of these vic-diorganometals is strongly affected by the nature of substituents present either on the aromatic ring(s) or on the carbanionic centers, and it can be correlated with their ability to delocalize the arylmethyl carbanions. These findings are supported by electrochemical analysis of the reduction behavior of the parent 1,2-diarylalkene. Applications of these results to the reduction of selected substrates are described. 2009 American Chemical Society.