51112-82-4

Upstream product

• 6118-51-0 exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 
• 6766-44-5 7-oxabicyclo<2.2.1>heptene-exo-2,3-dicarboxylic anhydride 
• 51112-81-3 endo, cis-7-oxabicyclo<2.2.1>hept-5-ene-2,3-dicarboxylic acid 

Downstream Products

• 109685-79-2 (1S,2S,6S,7R,8S,9S)-8-Chloro-9-(2,4-dinitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-78-1 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-(2,4-dinitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 6253-21-0 3α-hydroxymethyl-7α-oxabicyclo[2.2.1]heptane-2α-carboxylic acid lactone 
• 109685-77-0 (1R,2R,6R,7S,8R,9R)-8-Chloro-9-(2-nitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-76-9 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-(2-nitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-75-8 (1S,2S,6S,7R,8S,9S)-8-Chloro-9-phenylsulfanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-74-7 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-phenylsulfanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 135440-52-7 5-exo-(2'-diphenylphosphinoyl-1'-oxoethyl)-6-exo-hydroxymethyl-7-oxabicyclo<2.2.1>hept-2-ene hemiacetal 
• 119119-16-3 tert-Butyl-diphenyl-{(1R,2R,3R,4S)-3-[(E)-3-(tetrahydro-pyran-2-yloxy)-propenyl]-7-oxa-bicyclo[2.2.1]hept-5-en-2-ylmethoxy}-silane 
• 119119-26-5 tert-Butyl-diphenyl-(1-{(E)-2-[(1R,2S,3S,4S)-3-(tetrahydro-pyran-2-yloxymethyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-vinyl}-hexyloxy)-silane 
• 135440-55-0 6-exo-(3,5-dinitrobenzoyloxymethyl)-5-exo-vinyl-7-oxabicyclo<2.2.1>hept-2-ene 
• 135440-53-8 2-(Diphenyl-phosphinoyl)-1-((1R,2R,3S,4S)-3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)-ethanol 
• 109685-81-6 (1S,2S,6S,7R,8S,9S)-8-Chloro-9-phenylselanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-80-5 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-phenylselanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 

Relevant academic research and scientific papers

Metal hydride reductions of unsymmetrically substituted cyclic anhydrides attached to strained ring systems

A dramatic reversal in regioselectivity is observed in the metal hydride reduction of unsimmetrical cyclic anhydrides such as 2, 3, and 4 compared to cyclic anhydrides attached to bridged ring systems (e.g.1).The synthesis of model cyclic anhydrides attached to strained rings is described and the ratios of isomeric lactones obtained upon reduction with metal hydride are reported.On the basis of theoretical calculations and, taking into account the intrinsic reactivity of the carbonyl group, the antiperiplanar effect, and steric congestion, an explanation is offered for the regioselectivity observed in the reduction of these compounds.

Synthesis of thromboxane A2 analogue (+/-)-(9,11),(11,12)-dideoxa-(9,11a)-oxa thromboxane A2

A synthesis of the thromboxane A2 analogue, (+/-)-(9,11),(11,12)-dideoxa-(9,11a)-oxa-thromboxane A2 (TXA2) starting from the exo-adduct 3 of maleic anhydride and furan is described

A SIMPLE SYNTHESIS OF BICYCLOHEPTANE SYSTEM,A KEY POTENTIAL INTERMEDIATE FOR STABLE PROSTAGLANDIN H2 ANALOGUE

A simple and efficient synthesis of 6-cyanomethyl-1-methoxycarbonylbicycloheptane system leading to stable prostaglandin H2 analogue is described.