5112-65-2

Usage

InChI:InChI=1/C11H16O2Si/c1-14(2,3)10-6-4-9(5-7-10)8-11(12)13/h4-7H,8H2,1-3H3,(H,12,13)

Upstream product

• 106-43-4 para-chlorotoluene 
• 14062-25-0 Ethyl 4-bromophenylacetate 
• 124-38-9 carbon dioxide 
• 3728-43-6 p-(trimethylsilyl)toluene 

Downstream Products

• 116952-79-5 2-Brom-2-<4-(trimethylsilyl)phenyl>-N'-tosylacetohydrazid 
• 116952-85-3 α-Brom-N-tosyl-2-<4-(trimethylsilyl)phenyl>-acetohydrazonoylchlorid 
• 116952-91-1 N-<1-Chlor-2-<4-(trimethylsilyl)phenyl>ethenyl>-N-tosyldiazen 
• 116952-74-0 Brom<4-(trimethylsilyl)phenyl>acetylchlorid 
• 20119-68-0 (4-trimethylsilanyl-phenyl)-acetyl chloride 
• 57337-84-5 methyl 2-<3-(trimethylsilyl)phenyl>acetate 
• 20119-71-5 p-Trimethylsilylphenyl-acethydrazid 

Relevant academic research and scientific papers

USE OF T-TYPE CALCIUM CHANNEL BLOCKER FOR TREATING PRURITUS

A medicament for treating or preventing pruritus is provided. For the medicament for treating or preventing pruritus, a compound having a blocking action on Cav3.2T-type calcium channels represented by General Formulas (I) to (VI), a tautomer of the compo

T-TYPE CALCIUM CHANNEL BLOCKER

To provide a novel T-type calcium channel blocker. A compound represented by the following General Formula (I), a tautomer or a stereoisomer of the compound, a pharmaceutically acceptable salt of the compound, or a solvate of the compound, the tautomer, the stereoisomer, or the salt is used as a T-type calcium channel blocker. wherein A represents a phenyl which may have a substituent, a 4-membered to 6-membered heteroaryl ring composed of one to three identical or different heteroatoms selected from an oxygen atom, a sulfur atom, and a nitrogen atom and carbon atoms as ring-constituting atoms, or a heterocondensed ring composed of the heteroaryl ring and either a benzene ring or a 6-membered heteroaryl ring composed of one to two nitrogen atoms and carbon atoms, wherein the heteroaryl ring or the heterocondensed ring may have a substituent and is bonded to a nitrogen atom of the adjacent cyclic amino by means of a carbon atom constituting these rings; B represents a phenyl which may have a substituent, a 5-membered or 6-membered heteroaryl ring composed of one to three identical or different heteroatoms selected from an oxygen atom, a sulfur atom, and a nitrogen atom and carbon atoms as ring-constituting atoms, or a heterocondensed ring composed of the heteroaryl ring and either a benzene ring or a 6-membered heteroaryl ring composed of one to two nitrogen atoms and carbon atoms, wherein the heteroaryl ring or the heterocondensed ring may have a substituent and is bonded to the adjacent cyclopropyl ring by means of a carbon atom constituting these rings; R1 and R2, which may be identical or different, each represent a hydrogen atom, a halogen atom, or the like; R3 represents a hydrogen atom, a halogen atom, or the like; n and m, which may be identical or different, each represent 0 or 1; and p represents 1 or 2.