51123-60-5Relevant articles and documents
Benzyloxy-substituted, fused N-heterocycles, processes for their preparation, and their use as bradykinin receptor antagonists
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, (2008/06/13)
Benzyloxy-substituted, fused N-heterocycles, because of their ability to act as bradykinin receptor antagonists, have been found to be useful as therapeutics for the treatment and prevention of liver cirrhosis or Alzheimer''s disease. This application describes such compounds, as well as processes for their preparation and use. The compounds according to this invention include compounds of formula (I) STR1in which B, D, R 1, and R 2 have the meanings indicated herein.
Substituted benzonitriles
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, (2008/06/13)
An improved process for the preparation of 6-substituted-5-alkyl-2,4-quinazolinediamines, useful in the production of trimetrexate and similar antifolate agents, together with several novel intermediates are disclosed.