51145-18-7Relevant academic research and scientific papers
Palladium-catalyzed decarboxylative ortho-acylation of N-nitrosoanilines with α-oxocarboxylic acids
Yao, Jia-Ping,Wang, Guan-Wu
, p. 1687 - 1690 (2016)
A palladium-catalyzed efficient C-H acylation reaction of N-nitrosoanilines with α-oxocarboxylic acids has been developed. The reaction proceeded smoothly with potassium persulfate as the oxidant to afford acylated N-nitrosoanilines in moderate to good yi
Synthesis of 2-aminobenzophenones through acylation of anilines with α-oxocarboxylic acids assisted by: Tert -butyl nitrite
Wang, Qianqian,Zhang, Xinying,Fan, Xuesen
, p. 7737 - 7747 (2018/11/02)
In this paper, a regioselective, efficient and convenient synthesis of 2-aminobenzophenones through acylation of anilines with α-oxocarboxylic acids assisted by tert-butyl nitrite is presented. Interestingly, tert-butyl nitrite acts as not only an efficient and mild nitrosation reagent, but also a sustainable oxidant required in the Pd(ii)-catalyzed decarboxylative acylation. Meanwhile, the NO unit turned out to be an easily introduced and readily removable directing group for the regioselective acylation.
Palladium-catalyzed ortho-acylation of N-Nitrosoanilines with α-oxocarboxylic acids: A convenient method to synthesize N-Nitroso ketones and indazoles
Zhang, Liang,Wang, Zhe,Guo, Peiyu,Sun, Wei,Li, Ya-Min,Sun, Meng,Hua, Chengwen
, p. 2511 - 2514 (2016/05/24)
An efficient and mild protocol for regioselective synthesis of N-Nitroso aryl ketones by palladium-catalyzed direct acylation of arenes using N-Nitroso as directing groups is described. This reaction proceeded smoothly and could tolerate a variety of functional groups. Moreover, this chemistry offers a convenient access to a range of indazoles.
Palladium-catalyzed decarboxylative acylation of N-nitrosoanilines with α-oxocarboxylic acids
Wu, Yinuo,Sun, Lei,Chen, Yunyun,Zhou, Qian,Huang, Jia-Wu,Miao, Hui,Luo, Hai-Bin
, p. 1244 - 1250 (2016/02/19)
A palladium-catalyzed oxidative C-H bond decarboxylative acylation of N-nitrosoanilines using α-oxocarboxylic acid as the acyl source is described. The catalyst Pd(OAc)2 and oxidant (NH4)2S2O8 enabled ortho-acylation of N-nitrosoanilines at room temperature, affording an array of N-nitroso-2-aminobenzophenones in moderate to excellent yields.
