5115-19-5

Usage

Uses

Used in Agricultural Industry:
Glyphosate is used as a herbicide for controlling a wide range of weeds and grasses that compete with commercially grown crops. It is applied to inhibit the enzyme EPSPS, which is essential for the synthesis of aromatic amino acids in plants, thereby disrupting the plant's protein production and leading to the death of the target plant.
Used in Gardening Industry:
In gardening, glyphosate is used as a weed control agent to manage unwanted vegetation in gardens, lawns, and other landscaped areas. Its application helps maintain a clean and well-kept appearance by eliminating competing weeds and grasses.
However, it is important to note that the use of glyphosate has been a subject of controversy due to its potential environmental and health risks. As a result, some countries and regions have restricted or banned its use, and alternative weed control methods are being explored.

InChI:InChI=1/C3H8N3O5P/c4-3(5-1-2(7)8)6-12(9,10)11/h1H2,(H,7,8)(H5,4,5,6,9,10,11)

Upstream product

• 352-97-6 guanidineacetic acid 
• 88916-81-8 N-Phosphoryl-ω-methyl-isoharnstoff 
• 56-40-6 glycine 
• 109598-06-3 N-(diphenoxyphosphoryl-carbamimidoyl)-glycine 

Downstream Products

• 355119-49-2 [(HO)(O)P(O)NHC(NH)NHCH₂COOHCdCl]2 

Relevant academic research and scientific papers

Identification of amino acid residues responsible for taurocyamine binding in mitochondrial taurocyamine kinase from Arenicola brasiliensis

In order to investigate the residues associated with binding of the substrate taurocyamine in Arenicola mitochondrial taurocyamine kinase (TK), we performed Ala-scanning of the amino acid sequence HTKTV at positions 67-71 on the GS loop, and determined apparent Km and Vmax (appKm and appVmax, respectively) of the mutant forms for the substrates taurocyamine and glycocyamine. The appKm values for taurocyamine of the K69A, T70A and V71A mutants were significantly increased as compared with wild-type, suggesting that these residues are associated with taurocyamine binding. Of special interest is a property of V71A mutant: its catalytic efficiency for glycocyamine was twice that for taurocyamine, indicating that the V71A mutant acts like a glycocyamine kinase, rather than a TK. The role of the amino acid residue K95 of Arenicola MiTK was also examined. K95 was replaced with R, H, Y, I, A and E. K95R, K95H and K95I have a 3-fold higher affinity for taurocyamine, and activity was largely lost in K95E. On the other hand, the K95Y mutant showed a rather unique feature; namely, an increase in substrate concentration caused a decrease in initial velocity of the reaction (substrate inhibition). This is the first report on the key amino acid residues responsible for taurocyamine binding in mitochondrial TK.