511522-41-1 Usage
Uses
Used in Chemical Industry:
1-(4-DIMETHYLAMINOPHENYL)-2,2,2-TRIFLUOROETHYLAMINE is used as a chemical intermediate for the synthesis of various compounds due to its unique functional groups, which can be utilized in the development of new materials and products.
Used in Pharmaceutical Industry:
1-(4-DIMETHYLAMINOPHENYL)-2,2,2-TRIFLUOROETHYLAMINE is used as a building block in the design and synthesis of new pharmaceutical agents, potentially targeting specific biological pathways or receptors for therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 511522-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,1,5,2 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 511522-41:
(8*5)+(7*1)+(6*1)+(5*5)+(4*2)+(3*2)+(2*4)+(1*1)=101
101 % 10 = 1
So 511522-41-1 is a valid CAS Registry Number.
511522-41-1Relevant academic research and scientific papers
BF3-promoted aromatic substitution of N-alkyl α-trifluoromethylated imine: Facile synthesis of 1-aryl-2,2,2-trifluoroethylamines
Gong, Yuefa,Kato, Katsuya,Kimoto, Hiroshi
, p. 2637 - 2645 (2007/10/03)
The aromatic substitution of three representative N-alkyl trifluoromethyl imines 1a-c (R: a, benzyl; b, benzhydryl; c, methyl), obtained from primary alkyl amines and trifluoroacetaldehyde ethyl hemiacetal, was used to investigate the preparation of 1-aryl-2,2,2-trifluoroethylamines. In the presence of BF3·OEt2, the reaction of imine 1 with various aromatic compounds proceeded smoothly at room temperature, giving N-alkyl-1-aryl-2,2,2-trifluoroethylamines in moderate-to-high yields. Moreover, successful regioselective removal of N-benzyl and N-benzhydryl groups was achieved by hydrolysis in hydrochloric acid or by palladium-catalyzed hydrogenolysis.
