511534-45-5Relevant academic research and scientific papers
Enantioselective Alkynylation of Isatins: A Combination of Metal Catalysis and Organocatalysis
Jiang, Dan,Tang, Pei,Tan, Qiuyuan,Yang, Zhao,He, Ling,Zhang, Min
, p. 15830 - 15834 (2020)
An efficient and catalytic asymmetric alkynylation of isatins has been developed using a bifunctional amidophosphine-urea/AgBF4 complex as the catalyst. By a combination of metal catalysis and organocatalysis, excellent enantioselectivities (up to 99 % ee) and good yields are achieved. A wide range of both terminal alkynes and isatins are tolerated by this new catalyst system, providing access to structurally diverse propargylic alcohols with tetrasubstituted stereogenic centers in high efficiency.
A dual-catalysis approach to the kinetic resolution of 1,2-diaryl-1,2- diaminoethanes
Min, Chang,Mittal, Nisha,De, Chandra Kanta,Seidel, Daniel
supporting information, p. 10853 - 10855 (2012/11/07)
The kinetic resolution of racemic C2-symmetric 1,2-diaryl-1,2-diaminoethanes was accomplished for the first time through application of a dual-catalysis approach.
