511540-39-9Relevant academic research and scientific papers
Structure-activity relationship studies on a series of cyclohexylpiperazines bearing a phanylacetamide as ligands of the human melanocortin-4 receptor
Pontillo, Joseph,Tran, Joe A.,White, Nicole S.,Arellano, Melissa,Fleck, Beth A.,Marinkovic, Dragan,Tucci, Fabio C.,Saunders, John,Foster, Alan C.,Chen, Chen
, p. 5237 - 5240 (2007/10/03)
Synthesis and structure-activity relationship studies of a series of cyclohexylpiperazines bearing an amide side chain as ligands of the MC4 receptor are discussed. Compounds such as 11i from this series are potent agonists (EC50 = 33 nM, IA = 96%).
