511541-62-1Relevant academic research and scientific papers
RIP1K INHIBITORS
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Page/Page column 61, (2021/10/11)
Disclosed herein are kinase inhibitory compounds, such as a receptor-interacting protein-1 (RIP1) kinase inhibitor compounds, as well as pharmaceutical compositions and combinations comprising such inhibitory compounds. The disclosed compounds, pharmaceut
DIHYDROPYRIDONE UREAS AS P2X7 MODULATORS
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Page/Page column 63, (2010/07/04)
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES
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Page/Page column 112; 113, (2010/08/05)
The present invention relates to a compound according to formula I, wherein R1, R2 and A are as defined herein, which exhibit PDE4 inhibitory activity and may be used in the treatment of inflammatory diseases or autoimmune diseases,
Synthesis of micrococcinic acid
Ross Kelly,Jagoe,Gu
, p. 4263 - 4266 (2007/10/02)
The first synthesis of micrococcinic acid (2) is described. The five rings of 2 are assembled from monocyclic precursors using four palladium-catalyzed biaryl coupling reactions.
