511547-00-5

Upstream product

• 155193-73-0 tert-Butyl diazomalonyl chloride 
• 78-94-4 methyl vinyl ketone 
• 511261-25-9 (2S,4R)-1-(2-tert-Butoxycarbonyl-2-diazo-acetyl)-5-oxo-4-(3-phenyl-propyl)-pyrrolidine-2-carboxylic acid methyl ester 

Downstream Products

• 511261-60-2 (1R,3S)-8-Acetyl-5-oxo-1-(3-phenyl-propyl)-6-(toluene-3-sulfonylamino)-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester 
• 511261-47-5 (1R,3S)-8-Acetyl-6-tert-butoxycarbonylamino-5-oxo-1-(3-phenyl-propyl)-1,2,3,5-tetrahydro-indolizine-3-carboxylic acid methyl ester 
• 511261-30-6 (1R,3S)-8-Acetyl-5-oxo-1-(3-phenyl-propyl)-1,2,3,5-tetrahydro-indolizine-3,6-dicarboxylic acid 6-tert-butyl ester 3-methyl ester 
• 511261-28-2 (1R,3S)-8-Acetyl-6-hydroxy-5-oxo-1-(3-phenyl-propyl)-1,2,3,5,6,7-hexahydro-indolizine-3,6-dicarboxylic acid 6-tert-butyl ester 3-methyl ester 

Relevant academic research and scientific papers

Design and synthesis of 6-amino-5-oxo-1,2,3,5-tetrahydro-3-indolizinecarboxylic acids as β-sheet peptidomimetics

6-Amino-5-oxo-1,2,3,5-tetrahydro-3-indolizinecarboxylic acid was designed as a novel scaffold that can effectively mimic the extended conformation of a peptide. The key reaction in the synthesis of the scaffold involved a [3+2]-cycloaddition of a dicarbon