51165-09-4 Usage
Uses
Used in Pharmaceutical Industry:
SUBSTANCE P (5-11) is used as a therapeutic agent for its potential in pain management and the treatment of neuroinflammatory conditions. Its role in modulating pain signals and immune responses makes it a promising candidate for the development of new treatments for chronic pain, arthritis, and neurodegenerative diseases.
Used in Research and Development:
In the field of biomedical research, SUBSTANCE P (5-11) is utilized as a target for studying the underlying mechanisms of pain transmission and neuroinflammation. Further research on this neuropeptide may contribute to a better understanding of the pathophysiology of various pain-related and inflammatory disorders, potentially leading to the discovery of novel therapeutic approaches.
Check Digit Verification of cas no
The CAS Registry Mumber 51165-09-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,1,6 and 5 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 51165-09:
(7*5)+(6*1)+(5*1)+(4*6)+(3*5)+(2*0)+(1*9)=94
94 % 10 = 4
So 51165-09-4 is a valid CAS Registry Number.
InChI:InChI=1/C41H60N10O9S/c1-24(2)20-30(40(59)48-28(36(45)55)18-19-61-3)47-35(54)23-46-38(57)31(21-25-10-6-4-7-11-25)50-41(60)32(22-26-12-8-5-9-13-26)51-39(58)29(15-17-34(44)53)49-37(56)27(42)14-16-33(43)52/h4-13,24,27-32H,14-23,42H2,1-3H3,(H2,43,52)(H2,44,53)(H2,45,55)(H,46,57)(H,47,54)(H,48,59)(H,49,56)(H,50,60)(H,51,58)/t27-,28-,29-,30-,31-,32-/m0/s1
51165-09-4Relevant academic research and scientific papers
4-Methoxy-2,6-dimethylbenzenesulphonyl (Mds): a New Protecting Group of the Guanidino Function in Peptide Synthesis
Fujino, Masahiko,Nishimura, Osamu,Wakimasu, Mitsuhiro,Kitada, Chieko
, p. 668 - 669 (2007/10/02)
The 4-methoxy-2,6-dimethylbenzenesulphonyl (Mds) group for the protection of the guanidino function, which is readily removed with trifluoroacetic acid-thioanisole but is resistant to hydrogenolysis or treatment with dilute hydrogen chloride, can be used in the solution synthesis of arginine-containing peptides; this protecting group was effectively used in the synthesis of substance P and two LH-RH analogues.
