5117-16-8

Usage

Uses

Used in Semiconductor Industry:
1,1-Dimethyl-2-selenourea is used as a precursor for the synthesis of CdSe quantum dots in aqueous solutions. This application is significant because CdSe quantum dots have unique optical and electronic properties, making them valuable for various applications such as solar cells, light-emitting diodes, and photodetectors.
In the synthesis process, 1,1-Dimethyl-2-selenourea serves as a source of selenium, which is essential for the formation of CdSe quantum dots. The simultaneous illumination with a diode-pumped solid-state green laser and a Xe-Hg lamp facilitates the reaction, leading to the formation of high-quality quantum dots with desired properties.
Overall, 1,1-Dimethyl-2-selenourea plays a crucial role in the production of CdSe quantum dots, contributing to the advancement of semiconductor technology and the development of innovative electronic devices.

InChI:InChI=1/C3H7N2Se/c1-5(2)3(4)6/h4H,1-2H3

Upstream product

• 1467-79-4 NCNMe₂ 

Downstream Products

• 5533-45-9 2-dimethylamino-5-phenyl-selenazol-4-one 
• 154437-05-5 N,N-dimethyl-4-phenyl-1,3-selenazol-2-amine 
• 1384463-45-9 4-(2-(dimethylamino)-1,3-selenazol-4-yl)benzonitrile 

Relevant academic research and scientific papers

Inhibition of tyrosinase activity by N,N-unsubstituted selenourea derivatives

This study investigated inhibitory effects of N,N-unsubstituted selenourea derivatives on tyrosinase activity. Three types of N,N-unsubstituted selenoureas derivatives exhibited inhibitory effect on dopa (3,4-dihydroxyphenylalanine) oxidase activity of mushroom tyrosinase. Compound D at a concentration of 200/M exhibited 55.5% of inhibition on dopa oxidase activity of mushroom tyrosinase. This inhibitory effect was higher than that of kojic acid (39.4%), a well known tyrosinase inhibitor. Moreover, the compound D identified as a noncompetitive inhibitor by Lineweaver-Burk plot analysis. In addition, compound D also inhibited the melanin production in melan-a cells.

Selenoureas and thioureas are effective superoxide radical scavengers in vitro

Oxygen radicals, such as superoxide radicals, embellishing DNA, protein, lipids, etc., and carrying out the obstacle of the function of a cell is known. It depends for the oxidant level in the living body on the balance of a generation system and an elimination system of oxygen radicals, and research which controls an oxidant level in the living body is briskly done by taking in the substance which eliminates an oxygen radical. We investigated scavenging effects of superoxide radicals by selenoureas and thioureas using a highly sensitive and quantitative chemiluminescence method. At 330 nM, five selenoureas and five thioureas scavenged fractions of superoxide radicals (O 2-) ranging from 8.4% to 87.6%. Among five N,N-unsubstituted selenoureas and N,N-unsubstituted thioureas 1-selenocarbamoylpiperidine and 1-thiocarbamoylpyrrolidine were the most effective scavengers. A possibility that selenoureas could use it as a new superoxide anion-scavenging substance from the result of this research became clear.

A Simple Route to N,N-Disubstituted Selenoureas from N,N-Disubstituted Cyanamides

N,N-Disubstituted selenoureas 4 can be obtained in satisfactory yields by addition of an acid to a mixture of freshly prepared sodium selenide and N,N-disubstituted cyanamides 5.

Preparation of N,N-unsubstituted selenoureas and thioureas from cyanamides

Reaction of cyanamides with LiAlHSeH and LiAlHSH in the presence of HCl in diethyl ether provided the corresponding N,N-unsubstituted selenoureas and thioureas in moderate to high yields, respectively.

Preparation and characterisation of N,N-disubstituted 2-amino-selenazoles

As a result of checking suited methods for preparing N,N-disubstituted 2-amino-selenazoles 14 as a nearly unknown class of highly reactive selenazoles a simple route starting from N,N-disubstituted selenoureas 12 has been elaborated and used for the synthesis of a series of these compounds. The necessary selenium-containing starting compounds 12 are available from N,N-disubstituted cyanamides 18 and hydrogen selenide.

A Novel Synthesis of Primary Selenoamides from Nitriles by the Treatment of Bis(trimethylsilyl) Selenide and BF3*OEt2

Reaction of nitriles with (Me3Si)2Se in the presence of BF3*OEt2 afforded the corresponding primary selenoamides in moderate yields.A selenourea and a selenothiocarbamate were also prepared in a similar manner from the corresponding cyanamide and thiocyanate.