5118-94-5

Basic information

• Product Name: 3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE
• Synonyms: 3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE;3,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione;3,4-DIHYDRO-1H-1,4-BENZODIAZEPINE-2,5-DOINE;1H-1,4-Benzodiazepine-2,5(3H,4H)-dione;3,4-Dihydro-2H-1,4-benzodiazepine-2,5(1H)-dione;3,4-dihydro-1H-1,4-benzodiazepine-2,5-quinone;3H-1,4-Benzodiazepin-2,5(1H,4H)-dione
• CAS NO: 5118-94-5
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.17
• Mol File: 5118-94-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 537.4 ºC at 760 mmHg
• Flash Point: 259.3 ºC
• Appearance: /
• Density: 1.266 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE(5118-94-5)
• EPA Substance Registry System: 3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE(5118-94-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 5118-94-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 1807, 1989The Journal of Organic Chemistry, 27, p. 3606, 1962 DOI: 10.1021/jo01057a051

Upstream product

• 5946-43-0 2-(2-bromoacetylamino)benzoic acid methyl ester 

Downstream Products

• 5163-19-9 4-methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine 
• 620948-77-8 Benzyl 1,2,3,5-tetrahydro-4H-1,4-benzodiazepine-4-carboxylate 
• 1422029-29-5 5-benzyl-2-propyl-4H,5H-[1,3]oxazolo[4,5-c]quinolin-4-one 
• 174196-98-6 5-benzyl-2-methyl-4H,5H-[1,3]oxazolo[4,5-c]quinolin-4-one 
• 1422029-27-3 5-(2-phenylethyl)-2-(propan-2-yl)-4H,5H-[1,3]oxazolo[4,5-c]quinolin-4-one 
• 1422029-26-2 5-(2-phenylethyl)-2-propyl-4H,5H-[1,3]oxazolo[4,5-c]quinolin-4-one 
• 1422029-25-1 5-(2-phenylethyl)-2-methyl-4H,5H-[1,3]oxazolo[4,5-c]quinolin-4-one 
• 1422029-24-0 5-pentyl-2-phenyl-4H,5H-[1,3]oxazolo[4,5-c]quinolin-4-one 
• 5973-20-6 1-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione 
• 879789-09-0 1-(2-phenylethyl)-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione 
• 252259-67-9 2,3,4,5-tetrahydro-1-[1-oxo-2-(1-triphenylmethylimidazol-4-yl)ethyl]-4-[(1,1-dimethylethoxy)carbonyl]-1H-1,4-benzodiazepine 

Relevant articles and documents

Ring Closure Reactions of Methyl N-(Haloacetyl)anthranilates with Ammonia

In the presence of ammonia, methyl N-(bromoacetyl)anthranilate (4) is cyclized into 3H-1,4-benzodiazepine-2,5(1H,4H)-dione (1).However, when 4 is replaced with methyl N-(chloroacetyl)anthranilate (6), the only heterocyclic product formed in the reaction is 2-(chloromethyl)quinazoline-4(3H)-one (7).Under analogous conditions, 3-haloacetamidocrotonates (9,10) do not yield any heterocyclic products and no 1,4-diazepines can be obtained.