512186-39-9Relevant academic research and scientific papers
Nonsteroidal selective glucocorticoid modulators: The effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-lh-[1]benzopyrano[3,4-f]quinolines
Kym, Philip R.,Kort, Michael E.,Coghlan, Michael J.,Moore, Jimmie L.,Tang, Rui,Ratajczyk, James D.,Larson, Daniel P.,Elmore, Steven W.,Pratt, John K.,Stashko, Michael A.,Douglass Falls,Lin, Chun W.,Nakane, Masake,Miller, Loan,Tyree, Curtis M.,Miner, Jeffery N.,Jacobson, Peer B.,Wilcox, Denise M.,Nguyen, Phong,Lane, Benjamin C.
, p. 1016 - 1030 (2003)
The preparation and characterization of a series of C-10 substituted 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines as a novel class of selective ligands for the glucocorticoid receptor is described. Substitution at the C-10 positi
