51220-50-9

Usage

Uses

Used in Pharmaceutical Research:
DL-Norvaline methyl ester is used as a research compound for exploring its potential antioxidant and anti-inflammatory properties. Its application in this field is driven by the need to understand its effects on the body and its potential to contribute to the development of new drugs.
Used in Drug Development:
In the pharmaceutical industry, DL-Norvaline methyl ester is used as a precursor in the synthesis of new drugs. Its potential applications include the development of treatments for cardiovascular disease and cancer, although further research is necessary to fully comprehend its benefits and any possible side effects.
Overall, DL-Norvaline methyl ester is a promising compound with potential applications in medicine and health, warranting continued research to unlock its full potential.

Upstream product

• 67-56-1 methanol 
• 760-78-1 2-aminopentanoic acid 
• 106928-49-8 methyl (RS)-N-(benzyloxycarbonyl)-2-amino-4-pentenoate 
• 80758-65-2 α-Nitro-valeriansaeure-methylester 
• 57246-71-6 methyl pentanimidate 
• 21691-43-0 (R,S)-2-(N-benzyloxycarbonylamino)pentanoic acid 
• 110-59-8 pentanonitrile 

Downstream Products

• 6600-40-4 L-Norvaline 
• 29582-96-5 L-norvaline methyl ester 
• 21685-17-6 (R)-(-)-norvaline methyl ester 
• 2013-12-9 D-norvaline 
• 87974-75-2 (S)-α-methylnorvaline methyl ester 
• 1416726-89-0 C₃₇H₄₅N₅O₈ 
• 124094-91-3 2-{[1-Phenyl-meth-(E)-ylidene]-amino}-pentanoic acid methyl ester 
• 875568-99-3 2-{[(4-chlorophenyl)sulfonyl]amino}pentanoic acid methyl ester 
• 96943-10-1 methyl 2-(3-phenoxyphenyl)acetate 
• 40216-72-6 2-{[1-Phenyl-meth-(E)-ylidene]-amino}-pentanoic acid methyl ester 

Relevant academic research and scientific papers

TRIAZOLE DERIVATIVE

A compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof has an effect of inhibiting binding between S1P and its receptor Edg-1(S1P1), and is useful as a pharmaceutical product. (I) (In the formula, A represents a sulfur atom, an oxygen atom, a formula -SO- or a formula -SO2-; R1 represents a hydrogen atom, an alkyl group having 1-6 carbon atoms or the like; R2 represents an alkyl group having 1-6 carbon atoms, a cycloalkyl group having 3-8 carbon atoms or the like; R3 represents a hydrogen atom or an alkyl group having 1-6 carbon atoms; R4 represents a hydrogen atom, an alkyl group having 1-6 carbon atoms, a phenyl group or the like; R5 represents a hydrogen atom or an alkyl group having 1-6 carbon atoms; and R6 represents an alkyl group having 1-6 carbon atoms, a phenyl group or a substituted phenyl group.)

Squaric acid derivatives prevent the removal of N-Cbz and N-Fmoc groups under catalytic hydrogenation reaction

Under the catalytic hydrogenation conditions (H2/Pd-C), squaric acid derivatives 4 and 7 were found to be effective additives for chemoselective reduction of olefins and an alkyne having an N-Cbz or N-Fmoc group where the amino group remained to be protected. Benzyl esters having an N-Cbz or N-Fmoc group we re also selectively removed to give the corresponding N-protected carboxylic acids.

A Facile Synthesis of α-Amino Esters via Reduction of α-Nitro Esters Using Ammonium Formate as a Catalytic Hydrogen Transfer Agent

Various nitroesters 3 were selectively and rapidly reduced to their corresponding amino esters 4 in very good yield using anhydrous ammonium formate as a catalytic hydrogen transfer agent.