51224-51-2

Upstream product

• 5779-96-4 3-methoxy-2-(methoxymethyloxy)benzaldehyde 

Downstream Products

• 866535-19-5 1-bromomethyl-3-methoxy-2-methoxymethoxy-benzene 
• 73406-57-2 (3-Methoxy-2-methoxymethoxyphenyl)acetonitril 
• 1334171-01-5 C₁₃H₁₅NO₄ 
• 1334171-13-9 C₁₆H₁₇NO₅ 
• 1334171-11-7 C₂₂H₂₂INO₆ 
• 1334171-10-6 C₂₂H₂₂INO₆ 
• 1334529-17-7 C₂₂H₂₂BrNO₆ 
• 51224-52-3 2-methoxymethoxy-3-methoxybenzyl chloride 
• 866535-21-9 2-[(Z)-4-(3-Methoxy-2-methoxymethoxy-phenyl)-2-methyl-but-2-enyloxy]-tetrahydro-pyran 
• 866535-23-1 2-((Z)-4-Hydroxy-3-methyl-but-2-enyl)-6-methoxy-phenol 

Relevant academic research and scientific papers

Synthesis of two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids

Two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids, 6-hydroxy-3-methyl-8-(phenylethyl)-2,5-dihydro-1-benzoxepin-9-carboxylic acid (radulanin E) (1) and 9-hydroxy-3-methyl-2,5-dihydro-1-benzoxepin-7-carboxylic acid (2), were synthes

Asymmetric synthesis of bioactive hydrodibenzofuran alkaloids: (-)-lycoramine, (-)-galanthamine, and (+)-lunarine

Divergent route: A direct C-C bond-forming approach to the key aryl-substituted all-carbon quaternary stereogenic center present in bioactive hydrodibenzofuran alkaloids has been discovered. This approach involves an unprecedented organocatalytic enantioselective Michael addition of α-cyanoketones with acrylates (see scheme) and was used in a novel and divergent synthetic strategy for the title compounds in asymmetric fashion.

Synthesis and hydrolysis kinetics of 4-cyano-4-phenylpiperidine derivatives: A route to morphine analogs

A description is given of a high-yield synthesis leading to various hydroxy-2 phenylacetonitriles and to various benzodihydro-2,3 furannones-2. The intermediary 12 benzylic mesylates give quantitatively the corresponding 11 chlorides by the action of hydrochlorate of triethylamine; this procedure constitutes a very rewarding and easy method for chlorinating the benzylic alcohols in two stages without isolating the intermediary. A proximate effect has been shown which makes possible the hydrolysis of certain phenylacetonitriles by dilute acetic acid. This hydrolysis becomes very rapid when these nitriles are distributed; the increase of the speed of the hydrolysis illustrates the gem dialkyle effect.