51246-99-2Relevant academic research and scientific papers
The Reaction of N-Dichloromethylene-N,N-dialkylammonium Chlorides with Free Sugars: an Efficient Synthesis of Glycosyl Chlorides
Copeland, Christopher,McAdam, David P.,Stick, Robert V.
, p. 1239 - 1247 (2007/10/02)
The treatment of aldose derivatives that are protected at all but the anomeric hydroxy groups with N-dichloromethylene-N,N-dialkylammonium chlorides (alkyl = Me, Et) provides an improved method of preparing the corresponding glycosyl chlorides.Analogous derivatives containing an unprotected C1-C2 diol give 2-O-(N,N-dialkylcarbamoyl)glycosyl chlorides.
