51255-64-2Relevant academic research and scientific papers
Accessing Alkyl- and Alkenylcyclopentanes from Cr-Catalyzed Ethylene Oligomerization Using 2-Phosphinophosphinine Ligands
Newland, Robert J.,Smith, Alana,Smith, David M.,Fey, Natalie,Hanton, Martin J.,Mansell, Stephen M.
, p. 1062 - 1073 (2018/03/30)
Desilylation of the 2-phosphinophosphinine 2-PPh2-3-Me-6-SiMe3-PC5H2 with HCl gave 2-PPh2-3-Me-PC5H3, demonstrating the late-stage modification of this bidentate heterocyclic lig
Concerning the Mechanism of Grignard Reagent Formation. Evidence for Radical Escape and Return to the Surface of Magnesium
Ashby, E. C.,Oswald, John
, p. 6068 - 6076 (2007/10/02)
A study of the mechanism of formation of Grignard reagents using alkyl halide radical probes has been conducted.The effects of activation of the magnesium, temperature, concentration of the alkyl halide, magnesium to alkyl halide ratio, magnesium purity, the nature of the alkyl group, the nature of the halide group, and solvent (viscosity and basicity) on the formation of Grignard reagent were studied.The data obtained were used to test the earlier report by Garst that alkyl radicals, generated in the reaction of an alkyl halide with magnesium, diffuse freely into the solvent phase and return to the magnesium surface to form Grignard reagent.In this study cyclizable radical probes and radical traps were employed to study the extent to which radicals leave and return to the surface of magnesium to form Grignard reagent.In the particular system reported here, the data indicate that ca.25percent of the Grignard reagent is formed from radicals that diffuse into the solvent phase and than return to the magnesium surface to form Grignard reagent.
