51256-40-7

Upstream product

• 4358-87-6 (RS)-methyl mandelate 
• 98-59-9 p-toluenesulfonyl chloride 
• 22979-35-7 Methyl phenyldiazoacetate 
• 104-15-4 toluene-4-sulfonic acid 
• 27126-76-7 [hydroxy(tosyloxy)iodo]benzene 
• 40195-27-5 (1-methoxy-2-phenylvinyloxy)trimethylsilane 

Downstream Products

• 958852-30-7 (2S,αS)-α-(2-carbamoylpyrrolidin-1-yl)-α-phenylacetic acid methyl ester 
• 958852-31-8 (2S,αR)-α-(2-carbamoylpyrrolidin-1-yl)-α-phenylacetic acid methyl ester 
• 103615-36-7 5-methoxy-2-methyl-4-phenyl-1,3-oxazole 
• 64686-61-9 5-methoxy-2,4-diphenyl-oxazole 
• 1191446-36-2 (4S,9aS)-4-phenylperhydropyrido[1,2-a]pyrazine-1,3-dione 
• 1191446-34-0 (4R,9aS)-4-phenylperhydropyrido[1,2-a]pyrazine-1,3-dione 
• 1191446-35-1 (2S,αS)-α-(2-carbamoylpiperidinyl)-α-phenylacetic acid methyl ester 
• 1191446-33-9 (2S,αR)-α-(2-carbamoylpiperidinyl)-α-phenylacetic acid methyl ester 
• 101-41-7 benzeneacetic acid methyl ester 

Relevant academic research and scientific papers

Nonmetal catalyzed insertion reactions of diazocarbonyls to acid derivatives in fluorinated alcohols

The insertion reaction of diazocarbonyls to acids could be performed smoothly in fluorinated alcohols in the absence of metal catalyst. This new procedure allowed the chemoselective preparation of various functionalized compounds such as acyloxyesters, depsipeptides, and sulfonate, phosphonate, or boronate derivatives.

General, robust, and stereocomplementary preparation of β-ketoester enol tosylates as cross-coupling partners utilizing TsCl-N-methylimidazole agents

(Chemical Equation Presented) We have developed a general, robust, and cost-effective method for the (E)- or (Z)-stereocomplementary enol tosylation of β-ketoesters using TsCl-N-methylimidazole (NMI)-Et3N or LiOH. TsCl coupled with NMI formed a

Asymmetric tosylation of racemic 2-hydroxyalkanamides with chiral copper catalyst

Kinetic resolution of 2-hydroxyalkanamides was performed by tosylation in the presence of copper(II) triflate and (R,R)-Ph-BOX as a catalyst. This method was successfully applied to a variety of 2-hydroxyalkanamides in high enantioselectivity with up to 9

Reaction of benzene and benzene with Trimethylsilyl Enol Ethers. A New General Method for α-Sulfonyloxylation of Carbonyl Compounds

Reaction of benzene (1) with trimethylsilyl enol ethers of aromatic ketones 4a-d, alicyclic ketone 7, aliphatic ketone 10, and esters 13a-c in dichloromethane at room temperature gives good yields of α-(tosyloxy)carbonyl compounds 5