51265-34-0Relevant academic research and scientific papers
Synthesis of pyrrole N-derivatives from oxazolidines
Sadykov, E. Kh.,Stankevich,Lobanova,Klimenko
, p. 219 - 224 (2014/04/17)
Transformations of oxazolidine derivatives synthesized from industrially produced amino alcohols, aldehydes, and ketones under basic or acidic catalysis lead to the formation of N-alkyl- and N-(hydroxyalkyl)-substituted pyrroles in 19-81% yields.
Acid-catalyzed decomposition of cyclohexanespiro-2-oxazolidine
Kukharev
, p. 1482 - 1483 (2007/10/03)
Heating cyclohexanespiro-2-oxazolidine at 160-200°C in the presence of protic acids results in its decomposition to give N-(2-hydroxyethyl)cyclohexylamine, N-(2-hydroxyethyl)-4,5,6,7-tetrahydroindole, and 2-cyclohexylidenecyclohexanone. The possible pathways leading to these compounds are discussed.
OXAZOLIDINES. 1. BASIC CATALYTIC DISPROPORTIONATION OF CYCLOHEXANOSPIRO-2-OXAZOLIDINES: SYNTHESIS OF N-SUBSTITUTED 4,5,6,7-TETRAHYDROINDOLES
Kukharev, B.F.,Stankevich, V.K.,Kukhareva, V.A.
, p. 437 - 439 (2007/10/02)
It has been shown that the basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines in the presence of potasium hydroxide or sodium methylate leads to N-substituted 4,5,6,7-tetrahydroindoles with a yield of up to 73percent.The influence of the character of substituents at the nitrogen atom of oxazolidine on the course of the reaction has been established.
