51265-34-0

Basic information

• Product Name: N-(2-hydroxyethyl)-4,5,6,7-tetrahydro-1H-indole
• Synonyms: N-(2-hydroxyethyl)-4,5,6,7-tetrahydro-1H-indole
• CAS NO: 51265-34-0
• Molecular Weight: 165.235
• Mol File: 51265-34-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(2-hydroxyethyl)-4,5,6,7-tetrahydro-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-hydroxyethyl)-4,5,6,7-tetrahydro-1H-indole(51265-34-0)
• EPA Substance Registry System: N-(2-hydroxyethyl)-4,5,6,7-tetrahydro-1H-indole(51265-34-0)

Safety Data

• Hazardous Substances Data: 51265-34-0(Hazardous Substances Data)

Upstream product

• 177-04-8 1-oxa-4-azaspiro[4.5]decane 
• 141-43-5 ethanolamine 
• 2359-11-7 2-Spirocyclohexyl-3-(β-hydroxyethyl)oxazolidine 

Relevant articles and documents

Synthesis of pyrrole N-derivatives from oxazolidines

Transformations of oxazolidine derivatives synthesized from industrially produced amino alcohols, aldehydes, and ketones under basic or acidic catalysis lead to the formation of N-alkyl- and N-(hydroxyalkyl)-substituted pyrroles in 19-81% yields.

OXAZOLIDINES. 1. BASIC CATALYTIC DISPROPORTIONATION OF CYCLOHEXANOSPIRO-2-OXAZOLIDINES: SYNTHESIS OF N-SUBSTITUTED 4,5,6,7-TETRAHYDROINDOLES

It has been shown that the basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines in the presence of potasium hydroxide or sodium methylate leads to N-substituted 4,5,6,7-tetrahydroindoles with a yield of up to 73percent.The influence of the character of substituents at the nitrogen atom of oxazolidine on the course of the reaction has been established.